@article{6c117444d94348d4b48d32e52fe1a732,
title = "Intercalary heterochromatin in the genome of Drosophila",
abstract = "The modern concept of intercalary heterochromatin as polytene chromosome regions exhibiting a number of specific characteristics is formulated. DNA constituting these regions is replicated late in the S period; therefore, some strands of polytene chromosomes are underrepresented; i.e., they are underreplicated. Late-replicating regions account for about 7% of the genome; genes are located there in clusters of as many as 40. In general, the gene density in the clusters is substantially lower than in the main part of the genome. Late-replicating regions have an inactivating capacity: genes incorporated into these regions as parts of transposons are inactivated with a higher probability. These regions contain a specific protein SUUR affecting the rate of replication completion.",
author = "Zhimulev, {I. F.} and Belyaeva, {E. S.} and Andreeva, {E. N.} and Andreenkova, {N. G.} and Babenko, {V. N.} and Belyakin, {S. N.} and Boldyreva, {L. V.} and Brusentsova, {I. V.} and Demakov, {S. A.} and Demakova, {O. V.} and Zykov, {I. A.} and Kokoza, {E. B.} and Kolesnikova, {T. D.} and Maksimov, {D. A.} and Makunin, {I. V.} and Pindyurin, {A. V.} and Semeshin, {V. F.} and Khoroshko, {V. A.}",
note = "Funding Information: ACKNOWLEDGMENTS This study was supported by the Program of the Presidium of the Russian Academy of Sciences “Molecular and Cell Biology” (project no. 22.4), Integration Project of the Siberian Branch of the Rus sian Academy of Sciences (project no. 37), State Con tract with the Federal Agency for Science and Innova tions (contract no. 02.740.11.0099), and Russian Foundation for Basic Research (project nos. 08 04 00 635 a, 08 04 00 521 a, and 09 04 01 456 a).",
year = "2010",
doi = "10.1134/S1022795410100248",
language = "English (US)",
volume = "46",
pages = "1240--1242",
journal = "Russian Journal of Genetics",
issn = "1022-7954",
publisher = "Maik Nauka-Interperiodica Publishing",
number = "10",
}