Insight into catalytically relevant correlated motions in human purine nucleoside phosphorylase

Physics & Astronomy

• nucleosides 100%
• purines 97%
• enzymes 64%
• analogs 14%
• mutagenesis 13%
• catalysis 10%
• principal components analysis 5%
• cats 5%
• inhibitors 5%
• bears 5%
• centroids 5%
• ligands 4%
• monomers 4%
• simulation 3%
• molecular dynamics 3%
• kinetics 2%
• estimates 2%

Chemical Compounds

• Purine Nucleoside 83%
• Immucillin H 9%
• Catalysis 9%
• Simulation 6%
• Atomic Coordinate 6%
• Site-Directed Mutagenesis 5%
• Purine 5%
• Molecular Dynamics 3%
• Monomer 2%
• Crystal Structure 2%