Inhibition of protein synthesis in reticulocyte lysates by poliovirus

J. Racevskis; S. S. Kerwar; G. Koch

doi:10.1099/0022-1317-31-1-135

Inhibition of protein synthesis in reticulocyte lysates by poliovirus

J. Racevskis, S. S. Kerwar, G. Koch

Research output: Contribution to journal › Article › peer-review

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Abstract

Addition of 1 x 10¹⁰ p.f.u. purified poliovirus to 100 μl of a rabbit reticulocyte lysate protein synthesizing system causes a complete inhibition of initiation of protein synthesis. This inhibition is not due to the viral RNA nor to any contaminants of the preparation, but is most likely caused by the viral coat protein.

Original language	English (US)
Pages (from-to)	135-137
Number of pages	3
Journal	Journal of General Virology
Volume	31
Issue number	1
DOIs	https://doi.org/10.1099/0022-1317-31-1-135
State	Published - 1976
Externally published	Yes

ASJC Scopus subject areas

Virology

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10.1099/0022-1317-31-1-135

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title = "Inhibition of protein synthesis in reticulocyte lysates by poliovirus",

abstract = "Addition of 1 x 1010 p.f.u. purified poliovirus to 100 μl of a rabbit reticulocyte lysate protein synthesizing system causes a complete inhibition of initiation of protein synthesis. This inhibition is not due to the viral RNA nor to any contaminants of the preparation, but is most likely caused by the viral coat protein.",

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AB - Addition of 1 x 1010 p.f.u. purified poliovirus to 100 μl of a rabbit reticulocyte lysate protein synthesizing system causes a complete inhibition of initiation of protein synthesis. This inhibition is not due to the viral RNA nor to any contaminants of the preparation, but is most likely caused by the viral coat protein.

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Inhibition of protein synthesis in reticulocyte lysates by poliovirus

Abstract

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