Inhibition of protein synthesis in reticulocyte lysates by poliovirus

J. Racevskis, S. S. Kerwar, G. Koch

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Abstract

Addition of 1 x 1010 p.f.u. purified poliovirus to 100 μl of a rabbit reticulocyte lysate protein synthesizing system causes a complete inhibition of initiation of protein synthesis. This inhibition is not due to the viral RNA nor to any contaminants of the preparation, but is most likely caused by the viral coat protein.

Original languageEnglish (US)
Pages (from-to)135-137
Number of pages3
JournalJournal of General Virology
Volume31
Issue number1
Publication statusPublished - Dec 1 1976
Externally publishedYes

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ASJC Scopus subject areas

  • Virology

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