@article{78f0e257ce38489bb7c5632eafd46264,
title = "Inferring transient particle transport dynamics in live cells",
abstract = "Live-cell imaging and particle tracking provide rich information on mechanisms of intracellular transport. However, trajectory analysis procedures to infer complex transport dynamics involving stochastic switching between active transport and diffusive motion are lacking. We applied Bayesian model selection to hidden Markov modeling to infer transient transport states from trajectories of mRNA-protein complexes in live mouse hippocampal neurons and metaphase kinetochores in dividing human cells.",
author = "Nilah Monnier and Zachary Barry and Park, {Hye Yoon} and Su, {Kuan Chung} and Zachary Katz and English, {Brian P.} and Arkajit Dey and Keyao Pan and Cheeseman, {Iain M.} and Singer, {Robert H.} and Mark Bathe",
note = "Funding Information: Research reported in this publication was supported by grants from the US National Institutes of Health (NIH) National Institute of Mental Health (U01 MH106011) and the US National Science Foundation Physics of Living Systems (PHY 1305537) to M.B., an NIH grant from the National Institute of Neurological Diseases and Stroke (NS083085-19) to R.H.S., a Scholar award from the Leukemia & Lymphoma Society and an NIH grant from the National Institute of General Medical Sciences (GM088313) to I.M.C., and a Schroedinger fellowship from the Austrian Science Fund to K.-C.S. We also thank M. Linden for helpful discussions. Publisher Copyright: {\textcopyright} 2015 Nature America, Inc.",
year = "2015",
month = aug,
day = "28",
doi = "10.1038/nmeth.3483",
language = "English (US)",
volume = "12",
pages = "838--840",
journal = "Nature Methods",
issn = "1548-7091",
publisher = "Nature Publishing Group",
number = "9",
}