Infectious crystalline keratopathy with ring opacity

J. M. McDonnell, D. C. Gritz, D. Hwang, P. J. McDonnell

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11 Scopus citations

Abstract

A 41-year-old physician was treated for 3 months with antiviral medications, antibiotics, and steroids for presumed herpetic keratitis. When seen by us, an annular infiltrate was observed, along with crystalline-like opacities in the superficial one third of the stroma. Cultures of scrapings and of subsequent biopsies were positive for Streptococcus mitis of the viridans group; histopathology demonstrated large aggregates of cocci between the stroma lamellae. Tapering of topical corticosteroids and treatment with topical penicillin resulted in resolution of the infiltrates. The clinical appearance and findings in this patient suggest that infectious crystalline keratitis can produce an annular infiltrate. Injection of the organism into rabbit corneas produced a crystalline infiltrate, but no annular opacity was observed. Corticosteroids altered the clinical and histopathologic appearance of the lesions in rabbits.

Original languageEnglish (US)
Pages (from-to)479-483
Number of pages5
JournalCornea
Volume11
Issue number5
DOIs
Publication statusPublished - Jan 1 1992

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ASJC Scopus subject areas

  • Ophthalmology

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McDonnell, J. M., Gritz, D. C., Hwang, D., & McDonnell, P. J. (1992). Infectious crystalline keratopathy with ring opacity. Cornea, 11(5), 479-483. https://doi.org/10.1097/00003226-199209000-00020