Infection with Human T-Cell Leukemia Virus Type I in Patients with Leukemia

Kaye Kawahara, Eugene Yanagihara, Jeffrey M. Nakamura, Robert G. Westphal, Grace Y. Minamoto, Jonathan W.m. Gold, Klaus Mayer, Donald Armstrong

Research output: Contribution to journalLetter

2 Scopus citations

Abstract

To the Editor: Minamoto et al. (Jan. 28 issue)1 confirmed observations from Japan that blood transfusions can transmit human T-cell leukemia virus Type I (HTLV-I).2 We have previously reported a case in a 56-year-old Japanese woman from Hawaii who seroconverted to HTLV-I after induction and consolidation therapy for acute nonlymphocytic leukemia, during which she received a total of 20 units of packed red cells and 93 units of platelet concentrate. She remains free of physical and laboratory evidence of adult T-cell leukemia and of spastic paraparesis.3 Cell cultures have demonstrated active viral-antigen production. Her husband is serologically negative at this.

Original languageEnglish (US)
Pages (from-to)243-244
Number of pages2
JournalNew England Journal of Medicine
Volume319
Issue number4
DOIs
StatePublished - Jul 28 1988

ASJC Scopus subject areas

  • Medicine(all)

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    Kawahara, K., Yanagihara, E., Nakamura, J. M., Westphal, R. G., Minamoto, G. Y., Gold, J. W. M., Mayer, K., & Armstrong, D. (1988). Infection with Human T-Cell Leukemia Virus Type I in Patients with Leukemia. New England Journal of Medicine, 319(4), 243-244. https://doi.org/10.1056/NEJM198807283190411