Infection with human T-cell leukemia virus type I in patients with leukemia

Grace Y. Minamoto, J. W M Gold, D. A. Scheinberg, W. D. Hardy, N. Chein, E. Zuckerman, L. Reich, K. Dietz, T. Gee, J. Hoffer, K. Mayer, J. Gabrilove, B. Clarkson, D. Armstrong

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Abstract

Among 211 adults with leukemia who received multiple transfusions, 6 were found to be seropositive for human T-cell leukemia virus Type I (HTLV-I). Before the positive serum specimens were obtained, these patients received a mean of 14 units of red cells and 78 units of platelets. Seroconversion could be documented in three patients. None of the 6 patients seropositive for HTLV-I had a T-cell leukemia, other illnesses attributable to HTLV-I infection, or risk factors for HTLV-I infection other than transfusion: none were seropositive for human immunodeficiency virus. Patients with leukemia who receive multiple transfusions appear to be at risk for HTLV-I infection.

Original languageEnglish (US)
Pages (from-to)219-222
Number of pages4
JournalNew England Journal of Medicine
Volume318
Issue number4
StatePublished - 1988
Externally publishedYes

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Human T-lymphotropic virus 1
Leukemia
Infection
T-Cell Leukemia
Blood Platelets
HIV
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Minamoto, G. Y., Gold, J. W. M., Scheinberg, D. A., Hardy, W. D., Chein, N., Zuckerman, E., ... Armstrong, D. (1988). Infection with human T-cell leukemia virus type I in patients with leukemia. New England Journal of Medicine, 318(4), 219-222.

Infection with human T-cell leukemia virus type I in patients with leukemia. / Minamoto, Grace Y.; Gold, J. W M; Scheinberg, D. A.; Hardy, W. D.; Chein, N.; Zuckerman, E.; Reich, L.; Dietz, K.; Gee, T.; Hoffer, J.; Mayer, K.; Gabrilove, J.; Clarkson, B.; Armstrong, D.

In: New England Journal of Medicine, Vol. 318, No. 4, 1988, p. 219-222.

Research output: Contribution to journalArticle

Minamoto, GY, Gold, JWM, Scheinberg, DA, Hardy, WD, Chein, N, Zuckerman, E, Reich, L, Dietz, K, Gee, T, Hoffer, J, Mayer, K, Gabrilove, J, Clarkson, B & Armstrong, D 1988, 'Infection with human T-cell leukemia virus type I in patients with leukemia', New England Journal of Medicine, vol. 318, no. 4, pp. 219-222.
Minamoto GY, Gold JWM, Scheinberg DA, Hardy WD, Chein N, Zuckerman E et al. Infection with human T-cell leukemia virus type I in patients with leukemia. New England Journal of Medicine. 1988;318(4):219-222.
Minamoto, Grace Y. ; Gold, J. W M ; Scheinberg, D. A. ; Hardy, W. D. ; Chein, N. ; Zuckerman, E. ; Reich, L. ; Dietz, K. ; Gee, T. ; Hoffer, J. ; Mayer, K. ; Gabrilove, J. ; Clarkson, B. ; Armstrong, D. / Infection with human T-cell leukemia virus type I in patients with leukemia. In: New England Journal of Medicine. 1988 ; Vol. 318, No. 4. pp. 219-222.
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AU - Scheinberg, D. A.

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AU - Chein, N.

AU - Zuckerman, E.

AU - Reich, L.

AU - Dietz, K.

AU - Gee, T.

AU - Hoffer, J.

AU - Mayer, K.

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AU - Clarkson, B.

AU - Armstrong, D.

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