Infection rate following total joint arthroplasty in the HIV population

Brian M. Capogna; Andrew Lovy; Yossef Blum; Sun Jin Kim; Uriel R. Felsen; David S. Geller

doi:10.1016/j.arth.2012.12.021

Infection rate following total joint arthroplasty in the HIV population

Brian M. Capogna, Andrew Lovy, Yossef Blum, Sun Jin Kim, Uriel R. Felsen, David S. Geller

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P= 0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls ( P= 0.06 and P= 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.

Original language	English (US)
Pages (from-to)	1254-1258
Number of pages	5
Journal	Journal of Arthroplasty
Volume	28
Issue number	8
DOIs	https://doi.org/10.1016/j.arth.2012.12.021
State	Published - Sep 2013

Keywords

Arthroplasty
Hip
Human immunodeficiency virus (HIV)
Infection
Knee

ASJC Scopus subject areas

Orthopedics and Sports Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.arth.2012.12.021

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title = "Infection rate following total joint arthroplasty in the HIV population",

abstract = "The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P= 0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls ( P= 0.06 and P= 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.",

keywords = "Arthroplasty, Hip, Human immunodeficiency virus (HIV), Infection, Knee",

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AU - Lovy, Andrew

AU - Blum, Yossef

AU - Kim, Sun Jin

AU - Felsen, Uriel R.

AU - Geller, David S.

PY - 2013/9

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N2 - The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P= 0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls ( P= 0.06 and P= 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.

AB - The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P= 0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls ( P= 0.06 and P= 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.

KW - Arthroplasty

KW - Hip

KW - Human immunodeficiency virus (HIV)

KW - Infection

KW - Knee

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Infection rate following total joint arthroplasty in the HIV population

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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