TY - JOUR
T1 - Infantile digital fibroma
T2 - A rare fibromatosis
AU - Marks, Etan
AU - Ewart, Michelle
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/10
Y1 - 2016/10
N2 - Infantile digital fibroma is a rare benign lesion that usually occurs during the first 2 years of life. It can be multiple, but it is usually a single lesion. If it grows large enough it can cause joint deformities or interfere with everyday activities. Microscopically, the neoplastic cells usually have inclusion bodies that are best highlighted with a Masson trichrome stain but can often be seen on hematoxylin-eosin staining. Treatment for this entity is usually watchful waiting because of its ability to spontaneously regress, but excision is recommended if the lesion is symptomatic. More recently, fluorouracil or injectable steroids have shown great promise in inducing regression without the complications that accompany surgery.
AB - Infantile digital fibroma is a rare benign lesion that usually occurs during the first 2 years of life. It can be multiple, but it is usually a single lesion. If it grows large enough it can cause joint deformities or interfere with everyday activities. Microscopically, the neoplastic cells usually have inclusion bodies that are best highlighted with a Masson trichrome stain but can often be seen on hematoxylin-eosin staining. Treatment for this entity is usually watchful waiting because of its ability to spontaneously regress, but excision is recommended if the lesion is symptomatic. More recently, fluorouracil or injectable steroids have shown great promise in inducing regression without the complications that accompany surgery.
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U2 - 10.5858/arpa.2015-0492-RS
DO - 10.5858/arpa.2015-0492-RS
M3 - Review article
C2 - 27684985
AN - SCOPUS:84990177054
VL - 140
SP - 1157
EP - 1162
JO - Archives of Pathology and Laboratory Medicine
JF - Archives of Pathology and Laboratory Medicine
SN - 0003-9985
IS - 10
ER -