A new T3-specific RNA polymerase is found in T3-phage infected E. coli cells. Evidence is presented to show that the phage-induced polymerase is physically and biochemically distinct from the host cell RNA polymerase. The phage polymerase utilizes T3 DNA as template and is ineffective with T4, T7, calf thymus DNA or dAT copolymer. The polymerase can however copy dG: dC homopolymer, making poly rG exclusively.
|Original language||English (US)|
|Number of pages||8|
|Journal||Biochemical and Biophysical Research Communications|
|Publication status||Published - Apr 16 1971|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology