Indocyanine green dye enhanced vascular welding with the near infrared diode laser

M. C. Oz, Roy S. Chuck, J. P. Johnson, S. Parangi, L. S. Bass, R. Nowygrod, M. R. Treat

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

For vascular anastomosis, use of topical photosensitizing dye enhances selective delivery of laser energy to target tissue, thus reducing the amount of collateral thermal injury and threshold power required for welding. The authors compared the threshold power density needed to weld abdominal aortotomies in rabbits with and without photosensitizing dye. With continuous wave diode laser energy, the threshold for welding using the dye indocyanine green (ICG) was 150 mW (power density 4.8 watts/cm2 at spot diameter of 2 mm). Without dye enhancement, tissue effects were not observed even at the highest energy output available from the laser (300 mW, power density 9.6 watts/cm2). Immediately after welding, the mean bursting pressure for the welds was 260 mm Hg. In survival studies, no anastomotic ruptures, thomboses, or aneurysms were identified. Use of photosensitizing dyes for tissue welding is feasible and may allow arterial welding with lower power laser systems and cause less thermal trauma by lowering threshold power levels.

Original languageEnglish (US)
Pages (from-to)564-570
Number of pages7
JournalVascular Surgery
Volume24
Issue number8
StatePublished - 1990
Externally publishedYes

Fingerprint

Welding
Semiconductor Lasers
Indocyanine Green
Blood Vessels
Coloring Agents
Lasers
Hot Temperature
Wounds and Injuries
Aneurysm
Rupture
Rabbits
Pressure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Oz, M. C., Chuck, R. S., Johnson, J. P., Parangi, S., Bass, L. S., Nowygrod, R., & Treat, M. R. (1990). Indocyanine green dye enhanced vascular welding with the near infrared diode laser. Vascular Surgery, 24(8), 564-570.

Indocyanine green dye enhanced vascular welding with the near infrared diode laser. / Oz, M. C.; Chuck, Roy S.; Johnson, J. P.; Parangi, S.; Bass, L. S.; Nowygrod, R.; Treat, M. R.

In: Vascular Surgery, Vol. 24, No. 8, 1990, p. 564-570.

Research output: Contribution to journalArticle

Oz, MC, Chuck, RS, Johnson, JP, Parangi, S, Bass, LS, Nowygrod, R & Treat, MR 1990, 'Indocyanine green dye enhanced vascular welding with the near infrared diode laser', Vascular Surgery, vol. 24, no. 8, pp. 564-570.
Oz MC, Chuck RS, Johnson JP, Parangi S, Bass LS, Nowygrod R et al. Indocyanine green dye enhanced vascular welding with the near infrared diode laser. Vascular Surgery. 1990;24(8):564-570.
Oz, M. C. ; Chuck, Roy S. ; Johnson, J. P. ; Parangi, S. ; Bass, L. S. ; Nowygrod, R. ; Treat, M. R. / Indocyanine green dye enhanced vascular welding with the near infrared diode laser. In: Vascular Surgery. 1990 ; Vol. 24, No. 8. pp. 564-570.
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