Indications for heart transplantation in pediatric heart disease: A scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group

Charles E. Canter; Robert E. Shaddy; Daniel Bernstein; Daphne T. Hsu; Maryanne R.K. Chrisant; James K. Kirklin; Kirk R. Kanter; Robert S.D. Higgins; Elizabeth D. Blume; David N. Rosenthal; Mark M. Boucek; Karen C. Uzark; Allen H. Friedman; James K. Young

doi:10.1161/CIRCULATIONAHA.106.180449

Indications for heart transplantation in pediatric heart disease: A scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group

Charles E. Canter, Robert E. Shaddy, Daniel Bernstein, Daphne T. Hsu, Maryanne R.K. Chrisant, James K. Kirklin, Kirk R. Kanter, Robert S.D. Higgins, Elizabeth D. Blume, David N. Rosenthal, Mark M. Boucek, Karen C. Uzark, Allen H. Friedman, James K. Young

Research output: Contribution to journal › Article › peer-review

245 Scopus citations

Abstract

BACKGROUND - Since the initial utilization of heart transplantation as therapy for end-stage pediatric heart disease, improvements have occurred in outcomes with heart transplantation and surgical therapies for congenital heart disease along with the application of medical therapies to pediatric heart failure that have improved outcomes in adults. These events justify a reevaluation of the indications for heart transplantation in congenital heart disease and other causes of pediatric heart failure. METHODS AND RESULTS - A working group was commissioned to review accumulated experience with pediatric heart transplantation and its use in patients with unrepaired and/or previously repaired or palliated congenital heart disease (children and adults), in patients with pediatric cardiomyopathies, and in pediatric patients with prior heart transplantation. Evidence-based guidelines for the indications for heart transplantation or retransplantation for these conditions were developed. CONCLUSIONS - This evaluation has led to the development and refinement of indications for heart transplantation for patients with congenital heart disease and pediatric cardiomyopathies in addition to indications for pediatric heart retransplantation.

Original language	English (US)
Pages (from-to)	658-676
Number of pages	19
Journal	Circulation
Volume	115
Issue number	5
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.106.180449
State	Published - Feb 2007
Externally published	Yes

Keywords

AHA Scientific Statements
Pediatrics
Transplantation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1161/CIRCULATIONAHA.106.180449

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Canter, C. E., Shaddy, R. E., Bernstein, D., Hsu, D. T., Chrisant, M. R. K., Kirklin, J. K., Kanter, K. R., Higgins, R. S. D., Blume, E. D., Rosenthal, D. N., Boucek, M. M., Uzark, K. C., Friedman, A. H., & Young, J. K. (2007). Indications for heart transplantation in pediatric heart disease: A scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation, 115(5), 658-676. https://doi.org/10.1161/CIRCULATIONAHA.106.180449

Indications for heart transplantation in pediatric heart disease: A scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. / Canter, Charles E.; Shaddy, Robert E.; Bernstein, Daniel et al.
In: Circulation, Vol. 115, No. 5, 02.2007, p. 658-676.

Research output: Contribution to journal › Article › peer-review

Canter, CE, Shaddy, RE, Bernstein, D, Hsu, DT, Chrisant, MRK, Kirklin, JK, Kanter, KR, Higgins, RSD, Blume, ED, Rosenthal, DN, Boucek, MM, Uzark, KC, Friedman, AH & Young, JK 2007, 'Indications for heart transplantation in pediatric heart disease: A scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group', Circulation, vol. 115, no. 5, pp. 658-676. https://doi.org/10.1161/CIRCULATIONAHA.106.180449

Canter CE, Shaddy RE, Bernstein D, Hsu DT, Chrisant MRK, Kirklin JK et al. Indications for heart transplantation in pediatric heart disease: A scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007 Feb;115(5):658-676. doi: 10.1161/CIRCULATIONAHA.106.180449

Canter, Charles E. ; Shaddy, Robert E. ; Bernstein, Daniel et al. / Indications for heart transplantation in pediatric heart disease : A scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. In: Circulation. 2007 ; Vol. 115, No. 5. pp. 658-676.

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abstract = "BACKGROUND - Since the initial utilization of heart transplantation as therapy for end-stage pediatric heart disease, improvements have occurred in outcomes with heart transplantation and surgical therapies for congenital heart disease along with the application of medical therapies to pediatric heart failure that have improved outcomes in adults. These events justify a reevaluation of the indications for heart transplantation in congenital heart disease and other causes of pediatric heart failure. METHODS AND RESULTS - A working group was commissioned to review accumulated experience with pediatric heart transplantation and its use in patients with unrepaired and/or previously repaired or palliated congenital heart disease (children and adults), in patients with pediatric cardiomyopathies, and in pediatric patients with prior heart transplantation. Evidence-based guidelines for the indications for heart transplantation or retransplantation for these conditions were developed. CONCLUSIONS - This evaluation has led to the development and refinement of indications for heart transplantation for patients with congenital heart disease and pediatric cardiomyopathies in addition to indications for pediatric heart retransplantation.",

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AB - BACKGROUND - Since the initial utilization of heart transplantation as therapy for end-stage pediatric heart disease, improvements have occurred in outcomes with heart transplantation and surgical therapies for congenital heart disease along with the application of medical therapies to pediatric heart failure that have improved outcomes in adults. These events justify a reevaluation of the indications for heart transplantation in congenital heart disease and other causes of pediatric heart failure. METHODS AND RESULTS - A working group was commissioned to review accumulated experience with pediatric heart transplantation and its use in patients with unrepaired and/or previously repaired or palliated congenital heart disease (children and adults), in patients with pediatric cardiomyopathies, and in pediatric patients with prior heart transplantation. Evidence-based guidelines for the indications for heart transplantation or retransplantation for these conditions were developed. CONCLUSIONS - This evaluation has led to the development and refinement of indications for heart transplantation for patients with congenital heart disease and pediatric cardiomyopathies in addition to indications for pediatric heart retransplantation.

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