Independent domains of gait in older adults and associated motor and nonmotor attributes: Validation of a factor analysis approach

Sue Lord, Brook Galna, Joe Verghese, Shirley Coleman, David Burn, Lynn Rochester

Research output: Contribution to journalArticle

137 Citations (Scopus)

Abstract

Background.Gait is an important predictor of survival in older adults. Gait characteristics help to identify markers of incipient pathology, inform diagnostic algorithms and disease progression, and measure efficacy of interventions. However, there is no clear framework to guide selection of gait characteristics. This study developed and validated a model of gait in older adults based on a strong theoretical paradigm.Methods.One hundred and eighty-nine older adults with a mean (SD) age of 69.5 (7.6) years were assessed for 16 spatiotemporal gait variables using a 7-m instrumented walkway (GAITRite) while walking for 2 minutes. Principal components analysis and factor analysis "varimax" procedure were used to derive a model that was validated using a multimethod approach: replication of previous work; association of gait domains with motor, cognitive, and behavioral attributes; and discriminatory properties of gait domains using age as a criterion.Results.Five factors emerged from the principal components analysis: pace (22.5%), rhythm (19.3%), variability (15.1%), asymmetry (14.5%), and postural control (8.0%), explaining 79.5% of gait variance in total. Age, executive function, power of attention, balance self-efficacy, and physical fatigue were independently and selectively associated with 4 gait domains, explaining up to 40.1% of total variance. Median age discriminated pace, variability, and postural control domains.Conclusions. This study supports a 5-factor model of gait in older adults with domains that preferentially select for motor, cognitive, and behavioral attributes. Future research is required to validate the model. If successful, it will facilitate hypothesis-driven research to explain underlying gait mechanisms, identify contributory features to gait disturbance, and examine the effect of intervention.

Original languageEnglish (US)
Pages (from-to)820-827
Number of pages8
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume68
Issue number7
DOIs
StatePublished - Jul 2013

Fingerprint

Gait
Statistical Factor Analysis
Principal Component Analysis
Executive Function
Self Efficacy
Walking
Fatigue
Disease Progression
Pathology

Keywords

  • Factor analysis
  • Gait
  • Model.
  • Older adults

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology
  • Medicine(all)

Cite this

Independent domains of gait in older adults and associated motor and nonmotor attributes : Validation of a factor analysis approach. / Lord, Sue; Galna, Brook; Verghese, Joe; Coleman, Shirley; Burn, David; Rochester, Lynn.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 68, No. 7, 07.2013, p. 820-827.

Research output: Contribution to journalArticle

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