Independence of early speech processing from word meaning

Katherine E. Travis, Matthew K. Leonard, Alexander M. Chan, Christina Torres, Marisa L. Sizemore, Zhe Qu, Emad N. Eskandar, Anders M. Dale, Jeffrey L. Elman, Sydney S. Cash, Eric Halgren

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We combined magnetoencephalography (MEG) with magnetic resonance imaging and electrocorticography to separate in anatomy and latency 2 fundamental stages underlying speech comprehension. The first acoustic-phonetic stage is selective for words relative to control stimuli individually matched on acoustic properties. It begins ∼60 ms after stimulus onset and is localized to middle superior temporal cortex. It was replicated in another experiment, but is strongly dissociated from the response to tones in the same subjects. Within the same task, semantic priming of the same words by a related picture modulates cortical processing in a broader network, but this does not begin until ∼217 ms. The earlier onset of acoustic-phonetic processing compared with lexico-semantic modulation was significant in each individual subject. The MEG source estimates were confirmed with intracranial local field potential and high gamma power responses acquired in 2 additional subjects performing the same task. These recordings further identified sites within superior temporal cortex that responded only to the acoustic-phonetic contrast at short latencies, or the lexico-semantic at long. The independence of the early acoustic-phonetic response from semantic context suggests a limited role for lexical feedback in early speech perception.

Original languageEnglish (US)
Pages (from-to)2370-2379
Number of pages10
JournalCerebral Cortex
Volume23
Issue number10
DOIs
StatePublished - Oct 1 2013
Externally publishedYes

Fingerprint

Word Processing
Acoustics
Phonetics
Semantics
Magnetoencephalography
Temporal Lobe
Speech Perception
Anatomy
Magnetic Resonance Imaging

Keywords

  • ECoG
  • MEG
  • N400
  • Speech processing

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

Cite this

Travis, K. E., Leonard, M. K., Chan, A. M., Torres, C., Sizemore, M. L., Qu, Z., ... Halgren, E. (2013). Independence of early speech processing from word meaning. Cerebral Cortex, 23(10), 2370-2379. https://doi.org/10.1093/cercor/bhs228

Independence of early speech processing from word meaning. / Travis, Katherine E.; Leonard, Matthew K.; Chan, Alexander M.; Torres, Christina; Sizemore, Marisa L.; Qu, Zhe; Eskandar, Emad N.; Dale, Anders M.; Elman, Jeffrey L.; Cash, Sydney S.; Halgren, Eric.

In: Cerebral Cortex, Vol. 23, No. 10, 01.10.2013, p. 2370-2379.

Research output: Contribution to journalArticle

Travis, KE, Leonard, MK, Chan, AM, Torres, C, Sizemore, ML, Qu, Z, Eskandar, EN, Dale, AM, Elman, JL, Cash, SS & Halgren, E 2013, 'Independence of early speech processing from word meaning', Cerebral Cortex, vol. 23, no. 10, pp. 2370-2379. https://doi.org/10.1093/cercor/bhs228
Travis KE, Leonard MK, Chan AM, Torres C, Sizemore ML, Qu Z et al. Independence of early speech processing from word meaning. Cerebral Cortex. 2013 Oct 1;23(10):2370-2379. https://doi.org/10.1093/cercor/bhs228
Travis, Katherine E. ; Leonard, Matthew K. ; Chan, Alexander M. ; Torres, Christina ; Sizemore, Marisa L. ; Qu, Zhe ; Eskandar, Emad N. ; Dale, Anders M. ; Elman, Jeffrey L. ; Cash, Sydney S. ; Halgren, Eric. / Independence of early speech processing from word meaning. In: Cerebral Cortex. 2013 ; Vol. 23, No. 10. pp. 2370-2379.
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