TY - GEN
T1 - Increased phase synchronization between intracranial pressure and arterial blood pressure during elevated intracranial pressure in dogs
AU - Zou, R.
AU - McCormack, E.
AU - Egnor, M.
AU - Kim, D.
AU - Wagshul, M.
AU - MacDonald, B.
AU - Madsen, J. R.
PY - 2005
Y1 - 2005
N2 - We applied the concept of "phase synchronization" from nonlinear dynamics to the complex relationship between intracranial pressure (ICP) and arterial blood pressure (ABP) signals. This method is based on multiresolution wavelet transform (MRWT) in which the signals are divided into different frequency bands. We examined ICP and ABP signals from anaesthetized dogs, exploring normal ICP and elevated ICP by 1∼3 ml injection of saline into the cerebral ventricles. Phase synchronization analyses show an interesting phenomenon of phase reset from relatively uniform phase distribution to phase clustering around 0° after injection. To further quantitatively measure phase synchronization, phase coherence is used to distinguish the dynamics of normal ICP and elevated ICP by saline injection. Elevated ICP exhibits higher phase coherence than that of normal ICP, The results suggest that the association between ICP and ABP may involve nonlinear mechanisms of regulation. The clinical application of this method is in investigation.
AB - We applied the concept of "phase synchronization" from nonlinear dynamics to the complex relationship between intracranial pressure (ICP) and arterial blood pressure (ABP) signals. This method is based on multiresolution wavelet transform (MRWT) in which the signals are divided into different frequency bands. We examined ICP and ABP signals from anaesthetized dogs, exploring normal ICP and elevated ICP by 1∼3 ml injection of saline into the cerebral ventricles. Phase synchronization analyses show an interesting phenomenon of phase reset from relatively uniform phase distribution to phase clustering around 0° after injection. To further quantitatively measure phase synchronization, phase coherence is used to distinguish the dynamics of normal ICP and elevated ICP by saline injection. Elevated ICP exhibits higher phase coherence than that of normal ICP, The results suggest that the association between ICP and ABP may involve nonlinear mechanisms of regulation. The clinical application of this method is in investigation.
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U2 - 10.1109/iembs.2005.1616408
DO - 10.1109/iembs.2005.1616408
M3 - Conference contribution
AN - SCOPUS:33846908786
SN - 0780387406
SN - 9780780387409
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 315
EP - 318
BT - Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Y2 - 1 September 2005 through 4 September 2005
ER -