@article{461cd0ddba0c41dea8a67a8aa6957576,
title = "Increased incidence of renal cell carcinoma with hypertension",
abstract = "Of 276 patients who underwent evaluation to determine the cause of hypertension 2 were found to have unsuspected renal cell carcinoma. This prevalence of 0.73% is 16 times higher than expected for an age-matched population. Both patients exhibited abnormalities of plasma renin activity before radical nephrectomy but they remained hypertensive postoperatively. The data suggest an unexplained association between hypertension and renal cell carcinoma. Furthermore, abnormalities on excretory urograms in hypertensive people should be defined by selective renal arteriography.",
author = "A. Melman and Grim, {C. E.} and Weinberger, {M. H.}",
note = "Funding Information: The financial support of this work by NATO (Research Grant n'ES-003) is gratefully acknowledged. R.K. wishes to thank Prof. P. Kierkegaard for the use of the Philips PW 1100 diffractometer. D.L. wishes to thank the Institut pour 1'Encouragement de la Recherche Scientifique dans 1'Industrie et 1'Agriculture. We wish to thank Prof. C. Djerassi (Stanford University) for a high resolution mass spectrum and for the cd measurements; and Dr. J. Verseveldt (Netherlands) for the identification of the animal. The precious help of Dr. G. Germain and J.P. Declercq (Laboratoire de cristallographie et de Chimie Physique de l'universitg de Louvain, Belgium) is gratefully acknowledged.",
year = "1977",
doi = "10.1016/S0022-5347(17)58097-0",
language = "English (US)",
volume = "118",
pages = "531--532",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "4",
}