Increased allergic sensitization to mugwort in chronic urticaria

Gabriele De Vos, Evrydiki Kravvariti, Jennifer Collins, Anna Tavdy, Ramin Nazari, Golda Hudes, David Rosenstreich

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Background: Mugwort pollen is known to cross-react with a variety of spices and vegetables that are typically part of elimination diets used in the treatment of chronic urticaria (CU). Objective: We sought to investigate the association between CU and allergic sensitization to mugwort pollen. Methods: We conducted 2 case-control studies comparing aeroallergen skin prick test results between patients with and without CU and with or without allergic rhinitis (total n = 202). Results: CU patients with coexisting allergic rhinitis were more than twice as likely to be sensitized to mugwort as subjects not suffering from CU (67 vs. 30%; p = 0.004). Ragweed, cat, rat and mite sensitization were also significantly associated with CU. Overall, patients with CU had more positive aeroallergen skin tests than patients without CU (p < 0.005). Conclusion: Mugwort sensitization was associated with CU, possibly contributing to beneficial effect of elimination diets.

Original languageEnglish (US)
Pages (from-to)141-146
Number of pages6
JournalDermatology
Volume225
Issue number2
DOIs
StatePublished - Nov 1 2012

Keywords

  • Aeroallergen testing
  • Atopy
  • Chronic urticaria
  • Mugwort

ASJC Scopus subject areas

  • Dermatology

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