Incidental non-Hodgkin's lymphoma in patients with localized prostate cancer

Claus F. Eisenberger, Patrick C. Walsh, Mario A. Eisenberger, Nan Haw Chow, Alan W. Partin, Jacek L. Mostwin, Fray F. Marshall, Jonathan I. Epstein, Mark P. Schoenberg

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objectives. To determine the outcome of patients with clinically organ- confined prostate cancer undergoing radical retropubic prostatectomy for cure and incidentally discovered concurrent low-grade non-Hodgkin's lymphoma at time of surgery. Methods. From September 1986 to September 1997, 4319 patients underwent radical retropubic prostatectomy at our institution. The records of 10 patients incidentally diagnosed to have low-grade non-Hodgkin's lymphoma at the time of radical prostatectomy were retrospectively reviewed. Results. Of 4319 patients requiring radical prostatectomy, 10 (0.2%) were found to have low-grade non-Hodgkin's lymphoma. All 10 men had an uneventful postoperative course. Two patients subsequently developed progression of lymphoma, one of whom required treatment. One patient died of sepsis associated with his lymphoma and 1 patient died of an unrelated malignancy (lung cancer), both 7 years following surgery. Two patients developed biochemical prostate-specific antigen recurrence. The remainder of men were free of prostate Cancer recurrence and experienced no progression of lymphoma at an average of 45 months (range 12 to 142). Conclusions. Patients with organ-confined prostate cancer, who are candidates for radical prostatectomy, experience long-term prostate cancer-free survival in the face of incidentally diagnosed low-grade lymphoma. Because the management of most incidentally discovered low-grade lymphomas is expectant, patients discovered at surgery to have this clinical entity should not be denied radical prostatectomy.

Original languageEnglish (US)
Pages (from-to)175-179
Number of pages5
JournalUrology
Volume53
Issue number1
DOIs
StatePublished - Jan 1999
Externally publishedYes

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Non-Hodgkin's Lymphoma
Prostatic Neoplasms
Prostatectomy
Lymphoma
Recurrence
Prostate-Specific Antigen
Lung Neoplasms
Sepsis
Survival

ASJC Scopus subject areas

  • Urology

Cite this

Eisenberger, C. F., Walsh, P. C., Eisenberger, M. A., Chow, N. H., Partin, A. W., Mostwin, J. L., ... Schoenberg, M. P. (1999). Incidental non-Hodgkin's lymphoma in patients with localized prostate cancer. Urology, 53(1), 175-179. https://doi.org/10.1016/S0090-4295(98)00422-1

Incidental non-Hodgkin's lymphoma in patients with localized prostate cancer. / Eisenberger, Claus F.; Walsh, Patrick C.; Eisenberger, Mario A.; Chow, Nan Haw; Partin, Alan W.; Mostwin, Jacek L.; Marshall, Fray F.; Epstein, Jonathan I.; Schoenberg, Mark P.

In: Urology, Vol. 53, No. 1, 01.1999, p. 175-179.

Research output: Contribution to journalArticle

Eisenberger, CF, Walsh, PC, Eisenberger, MA, Chow, NH, Partin, AW, Mostwin, JL, Marshall, FF, Epstein, JI & Schoenberg, MP 1999, 'Incidental non-Hodgkin's lymphoma in patients with localized prostate cancer', Urology, vol. 53, no. 1, pp. 175-179. https://doi.org/10.1016/S0090-4295(98)00422-1
Eisenberger CF, Walsh PC, Eisenberger MA, Chow NH, Partin AW, Mostwin JL et al. Incidental non-Hodgkin's lymphoma in patients with localized prostate cancer. Urology. 1999 Jan;53(1):175-179. https://doi.org/10.1016/S0090-4295(98)00422-1
Eisenberger, Claus F. ; Walsh, Patrick C. ; Eisenberger, Mario A. ; Chow, Nan Haw ; Partin, Alan W. ; Mostwin, Jacek L. ; Marshall, Fray F. ; Epstein, Jonathan I. ; Schoenberg, Mark P. / Incidental non-Hodgkin's lymphoma in patients with localized prostate cancer. In: Urology. 1999 ; Vol. 53, No. 1. pp. 175-179.
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