In vitro synthesis of infectious DNA of murine leukaemia virus

Ellen Rothenberg, David Smotkin, David Baltimore, Robert A. Weinberg

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

DNA synthesised in vitro by purified virions of murine leukaemia virus is infectious. Neither RNA nor protein is required for infectivity. Transfection with reverse transcriptase product shows a single-hit dose response and results in the production of complete, infectious virus.

Original languageEnglish (US)
Pages (from-to)122-126
Number of pages5
JournalNature
Volume269
Issue number5624
DOIs
StatePublished - Dec 1 1977
Externally publishedYes

ASJC Scopus subject areas

  • General

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