In search of an "autophagomometer"

David C. Rubinsztein, Ana Maria Cuervo, Brinda Ravikumar, Sovan Sarkar, Viktor Korolchuk, Susmita Kaushik, Daniel J. Klionsky

Research output: Contribution to journalArticle

365 Citations (Scopus)

Abstract

Recent years have seen the realization that macroautophagy (which we will call autophagy) is not only important in yeast but is necessary for diverse functions in plants and animals. Importantly, autophagy can have an impact on human pathologies including infectious diseases, cancers, and neurodegenerative conditions.1 Thus, we need to be able to measure autophagy accurately in order to understand how it can be regulated physiologically and with exogenous agents.

Original languageEnglish (US)
Pages (from-to)585-589
Number of pages5
JournalAutophagy
Volume5
Issue number5
DOIs
StatePublished - Jul 1 2009

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Autophagy
Communicable Diseases
Yeasts
Pathology
Neoplasms

Keywords

  • Assay
  • Autophagy
  • Flux
  • LC3
  • Synthesis

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Rubinsztein, D. C., Cuervo, A. M., Ravikumar, B., Sarkar, S., Korolchuk, V., Kaushik, S., & Klionsky, D. J. (2009). In search of an "autophagomometer". Autophagy, 5(5), 585-589. https://doi.org/10.4161/auto.5.5.8823

In search of an "autophagomometer". / Rubinsztein, David C.; Cuervo, Ana Maria; Ravikumar, Brinda; Sarkar, Sovan; Korolchuk, Viktor; Kaushik, Susmita; Klionsky, Daniel J.

In: Autophagy, Vol. 5, No. 5, 01.07.2009, p. 585-589.

Research output: Contribution to journalArticle

Rubinsztein, DC, Cuervo, AM, Ravikumar, B, Sarkar, S, Korolchuk, V, Kaushik, S & Klionsky, DJ 2009, 'In search of an "autophagomometer"', Autophagy, vol. 5, no. 5, pp. 585-589. https://doi.org/10.4161/auto.5.5.8823
Rubinsztein DC, Cuervo AM, Ravikumar B, Sarkar S, Korolchuk V, Kaushik S et al. In search of an "autophagomometer". Autophagy. 2009 Jul 1;5(5):585-589. https://doi.org/10.4161/auto.5.5.8823
Rubinsztein, David C. ; Cuervo, Ana Maria ; Ravikumar, Brinda ; Sarkar, Sovan ; Korolchuk, Viktor ; Kaushik, Susmita ; Klionsky, Daniel J. / In search of an "autophagomometer". In: Autophagy. 2009 ; Vol. 5, No. 5. pp. 585-589.
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