In-home coal and wood use and lung cancer risk: A pooled analysis of the international lung cancer consortium

Howard D. Hosgood, Paolo Boffetta, Sander Greenland, Yuan Chin Amy Lee, John Mclaughlin, Adeline Seow, Eric J. Duell, Angeline S. Andrew, David Zaridze, Neonila Szeszenia-Dabrowska, Peter Rudnai, Jolanta Lissowska, Eleonóra Fabiánová, Dana Mates, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Hal Morgenstern, Nathaniel Rothman, Rayjean J. HungPaul Brennan, Qing Lan

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Background: Domestic fuel combustion from cooking and heating is an important public health issue because roughly 3 billion people are exposed worldwide. Recently, the International Agency for Research on Cancer classifed indoor emissions from household coal combustion as a human carcinogen (group 1) and from biomass fuel (primarily wood) as a probable human carcinogen (group 2A). oB je c t iv e s: We pooled seven studies from the International Lung Cancer Consortium (5,105 cases and 6,535 controls) to provide further epidemiological evaluation of the association between in-home solid-fuel use, particularly wood, and lung cancer risk. Methods: Using questionnaire data, we classifed subjects as predominant solid-fuel users (e.g., coal, wood) or nonsolid-fuel users (e.g., oil, gas, electricity). Unconditional logistic regression was used to estimate the odds ratios (ORs) and to compute 95% confdence intervals (CIs), adjusting for age, sex, education, smoking status, race/ethnicity, and study center. results: Compared with nonsolid-fuel users, predominant coal users (OR = 1.64; 95% CI, 1.49-1.81), particularly coal users in Asia (OR = 4.93; 95% CI, 3.73-6.52), and predominant wood users in North American and European countries (OR = 1.21; 95% CI, 1.06-1.38) experienced higher risk of lung cancer. Te results were similar in never-smoking women and other subgroups. conclusions: Our results are consistent with previous observations pertaining to in-home coal use and lung cancer risk, support the hypothesis of a carcinogenic potential of in-home wood use, and point to the need for more detailed study of factors afecting these associations.

Original languageEnglish (US)
Pages (from-to)1743-1747
Number of pages5
JournalEnvironmental Health Perspectives
Volume118
Issue number12
DOIs
StatePublished - Dec 2010
Externally publishedYes

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Coal
Lung Neoplasms
Odds Ratio
Carcinogens
Smoking
International Agencies
Electricity
Sex Education
Cooking
Biomass
Heating
Oils
Public Health
Gases
Logistic Models
Research
Neoplasms

Keywords

  • Coal
  • Lung cancer
  • Pooled
  • Risk factor
  • Wood

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Public Health, Environmental and Occupational Health

Cite this

In-home coal and wood use and lung cancer risk : A pooled analysis of the international lung cancer consortium. / Hosgood, Howard D.; Boffetta, Paolo; Greenland, Sander; Lee, Yuan Chin Amy; Mclaughlin, John; Seow, Adeline; Duell, Eric J.; Andrew, Angeline S.; Zaridze, David; Szeszenia-Dabrowska, Neonila; Rudnai, Peter; Lissowska, Jolanta; Fabiánová, Eleonóra; Mates, Dana; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Morgenstern, Hal; Rothman, Nathaniel; Hung, Rayjean J.; Brennan, Paul; Lan, Qing.

In: Environmental Health Perspectives, Vol. 118, No. 12, 12.2010, p. 1743-1747.

Research output: Contribution to journalArticle

Hosgood, HD, Boffetta, P, Greenland, S, Lee, YCA, Mclaughlin, J, Seow, A, Duell, EJ, Andrew, AS, Zaridze, D, Szeszenia-Dabrowska, N, Rudnai, P, Lissowska, J, Fabiánová, E, Mates, D, Bencko, V, Foretova, L, Janout, V, Morgenstern, H, Rothman, N, Hung, RJ, Brennan, P & Lan, Q 2010, 'In-home coal and wood use and lung cancer risk: A pooled analysis of the international lung cancer consortium', Environmental Health Perspectives, vol. 118, no. 12, pp. 1743-1747. https://doi.org/10.1289/ehp.1002217
Hosgood, Howard D. ; Boffetta, Paolo ; Greenland, Sander ; Lee, Yuan Chin Amy ; Mclaughlin, John ; Seow, Adeline ; Duell, Eric J. ; Andrew, Angeline S. ; Zaridze, David ; Szeszenia-Dabrowska, Neonila ; Rudnai, Peter ; Lissowska, Jolanta ; Fabiánová, Eleonóra ; Mates, Dana ; Bencko, Vladimir ; Foretova, Lenka ; Janout, Vladimir ; Morgenstern, Hal ; Rothman, Nathaniel ; Hung, Rayjean J. ; Brennan, Paul ; Lan, Qing. / In-home coal and wood use and lung cancer risk : A pooled analysis of the international lung cancer consortium. In: Environmental Health Perspectives. 2010 ; Vol. 118, No. 12. pp. 1743-1747.
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abstract = "Background: Domestic fuel combustion from cooking and heating is an important public health issue because roughly 3 billion people are exposed worldwide. Recently, the International Agency for Research on Cancer classifed indoor emissions from household coal combustion as a human carcinogen (group 1) and from biomass fuel (primarily wood) as a probable human carcinogen (group 2A). oB je c t iv e s: We pooled seven studies from the International Lung Cancer Consortium (5,105 cases and 6,535 controls) to provide further epidemiological evaluation of the association between in-home solid-fuel use, particularly wood, and lung cancer risk. Methods: Using questionnaire data, we classifed subjects as predominant solid-fuel users (e.g., coal, wood) or nonsolid-fuel users (e.g., oil, gas, electricity). Unconditional logistic regression was used to estimate the odds ratios (ORs) and to compute 95{\%} confdence intervals (CIs), adjusting for age, sex, education, smoking status, race/ethnicity, and study center. results: Compared with nonsolid-fuel users, predominant coal users (OR = 1.64; 95{\%} CI, 1.49-1.81), particularly coal users in Asia (OR = 4.93; 95{\%} CI, 3.73-6.52), and predominant wood users in North American and European countries (OR = 1.21; 95{\%} CI, 1.06-1.38) experienced higher risk of lung cancer. Te results were similar in never-smoking women and other subgroups. conclusions: Our results are consistent with previous observations pertaining to in-home coal use and lung cancer risk, support the hypothesis of a carcinogenic potential of in-home wood use, and point to the need for more detailed study of factors afecting these associations.",
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AU - Lee, Yuan Chin Amy

AU - Mclaughlin, John

AU - Seow, Adeline

AU - Duell, Eric J.

AU - Andrew, Angeline S.

AU - Zaridze, David

AU - Szeszenia-Dabrowska, Neonila

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AU - Janout, Vladimir

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N2 - Background: Domestic fuel combustion from cooking and heating is an important public health issue because roughly 3 billion people are exposed worldwide. Recently, the International Agency for Research on Cancer classifed indoor emissions from household coal combustion as a human carcinogen (group 1) and from biomass fuel (primarily wood) as a probable human carcinogen (group 2A). oB je c t iv e s: We pooled seven studies from the International Lung Cancer Consortium (5,105 cases and 6,535 controls) to provide further epidemiological evaluation of the association between in-home solid-fuel use, particularly wood, and lung cancer risk. Methods: Using questionnaire data, we classifed subjects as predominant solid-fuel users (e.g., coal, wood) or nonsolid-fuel users (e.g., oil, gas, electricity). Unconditional logistic regression was used to estimate the odds ratios (ORs) and to compute 95% confdence intervals (CIs), adjusting for age, sex, education, smoking status, race/ethnicity, and study center. results: Compared with nonsolid-fuel users, predominant coal users (OR = 1.64; 95% CI, 1.49-1.81), particularly coal users in Asia (OR = 4.93; 95% CI, 3.73-6.52), and predominant wood users in North American and European countries (OR = 1.21; 95% CI, 1.06-1.38) experienced higher risk of lung cancer. Te results were similar in never-smoking women and other subgroups. conclusions: Our results are consistent with previous observations pertaining to in-home coal use and lung cancer risk, support the hypothesis of a carcinogenic potential of in-home wood use, and point to the need for more detailed study of factors afecting these associations.

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