Improvements in Depression and Changes in Fatigue: Results from the SLAM DUNC Depression Treatment Trial

Julie Barroso; Angela M. Bengtson; Bradley N. Gaynes; Teena McGuinness; Evelyn B. Quinlivan; Michelle Ogle; Amy Heine; Nathan M. Thielman; Brian W. Pence

doi:10.1007/s10461-015-1242-4

Improvements in Depression and Changes in Fatigue: Results from the SLAM DUNC Depression Treatment Trial

Julie Barroso, Angela M. Bengtson, Bradley N. Gaynes, Teena McGuinness, Evelyn B. Quinlivan, Michelle Ogle, Amy Heine, Nathan M. Thielman, Brian W. Pence

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Fatigue and depression are common co-morbid conditions among people with HIV infection. We analyzed a population of HIV-infected adults with depression, who were enrolled in a depression treatment trial, to examine the extent to which improvements in depression over time were associated with improvements in HIV-related fatigue. Data for this analysis come from a randomized controlled trial to evaluate the effectiveness of improved depression treatment on antiretroviral adherence. Fatigue was measured using the HIV-Related Fatigue Scale, and depressive symptoms were measured with the Hamilton Depression Rating Scale. Participants (n = 234) were on average nearly 44 years of age and predominantly male, black or African American, and unemployed. Individuals who experienced stronger depression response (i.e., greater improvement in depression score) had larger decreases in fatigue. However, even among those who demonstrated a full depression response, nearly three-quarters continued to have either moderate or severe fatigue at 6 and 12 months.

Original language	English (US)
Pages (from-to)	235-242
Number of pages	8
Journal	AIDS and Behavior
Volume	20
Issue number	2
DOIs	https://doi.org/10.1007/s10461-015-1242-4
State	Published - Feb 1 2016
Externally published	Yes

Keywords

Depression
Fatigue
Intervention
Syndemic

ASJC Scopus subject areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10461-015-1242-4

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title = "Improvements in Depression and Changes in Fatigue: Results from the SLAM DUNC Depression Treatment Trial",

abstract = "Fatigue and depression are common co-morbid conditions among people with HIV infection. We analyzed a population of HIV-infected adults with depression, who were enrolled in a depression treatment trial, to examine the extent to which improvements in depression over time were associated with improvements in HIV-related fatigue. Data for this analysis come from a randomized controlled trial to evaluate the effectiveness of improved depression treatment on antiretroviral adherence. Fatigue was measured using the HIV-Related Fatigue Scale, and depressive symptoms were measured with the Hamilton Depression Rating Scale. Participants (n = 234) were on average nearly 44 years of age and predominantly male, black or African American, and unemployed. Individuals who experienced stronger depression response (i.e., greater improvement in depression score) had larger decreases in fatigue. However, even among those who demonstrated a full depression response, nearly three-quarters continued to have either moderate or severe fatigue at 6 and 12 months.",

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doi = "10.1007/s10461-015-1242-4",

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AU - Barroso, Julie

AU - Bengtson, Angela M.

AU - Gaynes, Bradley N.

AU - McGuinness, Teena

AU - Quinlivan, Evelyn B.

AU - Ogle, Michelle

AU - Heine, Amy

AU - Thielman, Nathan M.

AU - Pence, Brian W.

PY - 2016/2/1

Y1 - 2016/2/1

N2 - Fatigue and depression are common co-morbid conditions among people with HIV infection. We analyzed a population of HIV-infected adults with depression, who were enrolled in a depression treatment trial, to examine the extent to which improvements in depression over time were associated with improvements in HIV-related fatigue. Data for this analysis come from a randomized controlled trial to evaluate the effectiveness of improved depression treatment on antiretroviral adherence. Fatigue was measured using the HIV-Related Fatigue Scale, and depressive symptoms were measured with the Hamilton Depression Rating Scale. Participants (n = 234) were on average nearly 44 years of age and predominantly male, black or African American, and unemployed. Individuals who experienced stronger depression response (i.e., greater improvement in depression score) had larger decreases in fatigue. However, even among those who demonstrated a full depression response, nearly three-quarters continued to have either moderate or severe fatigue at 6 and 12 months.

AB - Fatigue and depression are common co-morbid conditions among people with HIV infection. We analyzed a population of HIV-infected adults with depression, who were enrolled in a depression treatment trial, to examine the extent to which improvements in depression over time were associated with improvements in HIV-related fatigue. Data for this analysis come from a randomized controlled trial to evaluate the effectiveness of improved depression treatment on antiretroviral adherence. Fatigue was measured using the HIV-Related Fatigue Scale, and depressive symptoms were measured with the Hamilton Depression Rating Scale. Participants (n = 234) were on average nearly 44 years of age and predominantly male, black or African American, and unemployed. Individuals who experienced stronger depression response (i.e., greater improvement in depression score) had larger decreases in fatigue. However, even among those who demonstrated a full depression response, nearly three-quarters continued to have either moderate or severe fatigue at 6 and 12 months.

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KW - Fatigue

KW - Intervention

KW - Syndemic

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Improvements in Depression and Changes in Fatigue: Results from the SLAM DUNC Depression Treatment Trial

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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