Improved exercise tolerance with long-term parenteral nutrition in cystic fibrosis

B. Skeie, J. Askanazi, M. M. Rothkopf, S. H. Rosenbaum, Vladimir Kvetan, E. Ross

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Two cystic fibrosis (CF) patients with severe pulmonary disease and malnutrition were followed during a course of long-term home total parenteral nutrition (TPN), which included iv fat emulsion. They gained 7 and 12 kg in body weight, respectively, and their ability to participate in daily activities increased. Progressive exercise testing before and during TPN showed a marked increase in maximal work load: 100% and 30%, respectively. At any given work load, oxygen uptake was increased while the respiratory quotient remained lower after the course of TPN. We believe that the lower respiratory quotient and greater oxygen consumption during exercise were due to a reduction in anaerobic metabolism after TNP.

Original languageEnglish (US)
Pages (from-to)960-962
Number of pages3
JournalCritical Care Medicine
Volume15
Issue number10
StatePublished - 1987
Externally publishedYes

Fingerprint

Exercise Tolerance
Total Parenteral Nutrition
Parenteral Nutrition
Workload
Cystic Fibrosis
Home Total Parenteral Nutrition
Exercise
Anaerobiosis
Emulsions
Oxygen Consumption
Malnutrition
Lung Diseases
Fats
Body Weight
Oxygen

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Skeie, B., Askanazi, J., Rothkopf, M. M., Rosenbaum, S. H., Kvetan, V., & Ross, E. (1987). Improved exercise tolerance with long-term parenteral nutrition in cystic fibrosis. Critical Care Medicine, 15(10), 960-962.

Improved exercise tolerance with long-term parenteral nutrition in cystic fibrosis. / Skeie, B.; Askanazi, J.; Rothkopf, M. M.; Rosenbaum, S. H.; Kvetan, Vladimir; Ross, E.

In: Critical Care Medicine, Vol. 15, No. 10, 1987, p. 960-962.

Research output: Contribution to journalArticle

Skeie, B, Askanazi, J, Rothkopf, MM, Rosenbaum, SH, Kvetan, V & Ross, E 1987, 'Improved exercise tolerance with long-term parenteral nutrition in cystic fibrosis', Critical Care Medicine, vol. 15, no. 10, pp. 960-962.
Skeie B, Askanazi J, Rothkopf MM, Rosenbaum SH, Kvetan V, Ross E. Improved exercise tolerance with long-term parenteral nutrition in cystic fibrosis. Critical Care Medicine. 1987;15(10):960-962.
Skeie, B. ; Askanazi, J. ; Rothkopf, M. M. ; Rosenbaum, S. H. ; Kvetan, Vladimir ; Ross, E. / Improved exercise tolerance with long-term parenteral nutrition in cystic fibrosis. In: Critical Care Medicine. 1987 ; Vol. 15, No. 10. pp. 960-962.
@article{baf867e2aa2b4c2aa5db5a066dfa93fb,
title = "Improved exercise tolerance with long-term parenteral nutrition in cystic fibrosis",
abstract = "Two cystic fibrosis (CF) patients with severe pulmonary disease and malnutrition were followed during a course of long-term home total parenteral nutrition (TPN), which included iv fat emulsion. They gained 7 and 12 kg in body weight, respectively, and their ability to participate in daily activities increased. Progressive exercise testing before and during TPN showed a marked increase in maximal work load: 100{\%} and 30{\%}, respectively. At any given work load, oxygen uptake was increased while the respiratory quotient remained lower after the course of TPN. We believe that the lower respiratory quotient and greater oxygen consumption during exercise were due to a reduction in anaerobic metabolism after TNP.",
author = "B. Skeie and J. Askanazi and Rothkopf, {M. M.} and Rosenbaum, {S. H.} and Vladimir Kvetan and E. Ross",
year = "1987",
language = "English (US)",
volume = "15",
pages = "960--962",
journal = "Critical Care Medicine",
issn = "0090-3493",
publisher = "Lippincott Williams and Wilkins",
number = "10",

}

TY - JOUR

T1 - Improved exercise tolerance with long-term parenteral nutrition in cystic fibrosis

AU - Skeie, B.

AU - Askanazi, J.

AU - Rothkopf, M. M.

AU - Rosenbaum, S. H.

AU - Kvetan, Vladimir

AU - Ross, E.

PY - 1987

Y1 - 1987

N2 - Two cystic fibrosis (CF) patients with severe pulmonary disease and malnutrition were followed during a course of long-term home total parenteral nutrition (TPN), which included iv fat emulsion. They gained 7 and 12 kg in body weight, respectively, and their ability to participate in daily activities increased. Progressive exercise testing before and during TPN showed a marked increase in maximal work load: 100% and 30%, respectively. At any given work load, oxygen uptake was increased while the respiratory quotient remained lower after the course of TPN. We believe that the lower respiratory quotient and greater oxygen consumption during exercise were due to a reduction in anaerobic metabolism after TNP.

AB - Two cystic fibrosis (CF) patients with severe pulmonary disease and malnutrition were followed during a course of long-term home total parenteral nutrition (TPN), which included iv fat emulsion. They gained 7 and 12 kg in body weight, respectively, and their ability to participate in daily activities increased. Progressive exercise testing before and during TPN showed a marked increase in maximal work load: 100% and 30%, respectively. At any given work load, oxygen uptake was increased while the respiratory quotient remained lower after the course of TPN. We believe that the lower respiratory quotient and greater oxygen consumption during exercise were due to a reduction in anaerobic metabolism after TNP.

UR - http://www.scopus.com/inward/record.url?scp=0023579148&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023579148&partnerID=8YFLogxK

M3 - Article

VL - 15

SP - 960

EP - 962

JO - Critical Care Medicine

JF - Critical Care Medicine

SN - 0090-3493

IS - 10

ER -