Abstract
Background Whether ablation of non-pulmonary vein (PV) triggers after pulmonary vein antrum isolation (PVAI) improves the long-term procedure outcome in patients with paroxysmal atrial fibrillation (PAF) and left ventricular systolic dysfunction is unknown. Objective We sought to evaluate whether a more extensive ablation procedure improves outcomes at follow-up. Methods Consecutive patients with PAF refractory to antiarrhythmic drugs presenting for PVAI were prospectively studied. Patients were categorized into 2 groups: patients with left ventricular ejection fraction (LVEF) ≤35% (group I; n = 175) and patients with LVEF ≥50% (group II; n = 545). Patients in group I were further divided according to whether additional ablation of non-PV triggers was performed (group IA; n = 88) or not (group IB; n = 87). Long-term ablation success off antiarrhythmic drugs after a single procedure was analyzed. Results Patients in group I had more non-PV triggers than did patients in group II (69.1% vs 26.6%; P
| Original language | English (US) |
|---|---|
| Pages (from-to) | 141-149 |
| Number of pages | 9 |
| Journal | Heart Rhythm |
| Volume | 13 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2016 |
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Keywords
- Atrial fibrillation
- Catheter ablation
- Ejection fraction
- Heart failure
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Physiology (medical)
Cite this
Importance of non-pulmonary vein triggers ablation to achieve long-term freedom from paroxysmal atrial fibrillation in patients with low ejection fraction. / Zhao, Yonghui; Di Biase, Luigi; Trivedi, Chintan; Mohanty, Sanghamitra; Bai, Rong; Mohanty, Prasant; Gianni, Carola; Santangeli, Pasquale; Horton, Rodney; Sanchez, Javier; Gallinghouse, G. Joseph; Zagrodzky, Jason; Hongo, Richard; Beheiry, Salwa; Lakkireddy, Dhanunjaya; Reddy, Madhu; Hranitzky, Patrick; Al-Ahmad, Amin; Elayi, Claude; Burkhardt, J. David; Natale, Andrea.
In: Heart Rhythm, Vol. 13, No. 1, 01.01.2016, p. 141-149.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Importance of non-pulmonary vein triggers ablation to achieve long-term freedom from paroxysmal atrial fibrillation in patients with low ejection fraction
AU - Zhao, Yonghui
AU - Di Biase, Luigi
AU - Trivedi, Chintan
AU - Mohanty, Sanghamitra
AU - Bai, Rong
AU - Mohanty, Prasant
AU - Gianni, Carola
AU - Santangeli, Pasquale
AU - Horton, Rodney
AU - Sanchez, Javier
AU - Gallinghouse, G. Joseph
AU - Zagrodzky, Jason
AU - Hongo, Richard
AU - Beheiry, Salwa
AU - Lakkireddy, Dhanunjaya
AU - Reddy, Madhu
AU - Hranitzky, Patrick
AU - Al-Ahmad, Amin
AU - Elayi, Claude
AU - Burkhardt, J. David
AU - Natale, Andrea
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Background Whether ablation of non-pulmonary vein (PV) triggers after pulmonary vein antrum isolation (PVAI) improves the long-term procedure outcome in patients with paroxysmal atrial fibrillation (PAF) and left ventricular systolic dysfunction is unknown. Objective We sought to evaluate whether a more extensive ablation procedure improves outcomes at follow-up. Methods Consecutive patients with PAF refractory to antiarrhythmic drugs presenting for PVAI were prospectively studied. Patients were categorized into 2 groups: patients with left ventricular ejection fraction (LVEF) ≤35% (group I; n = 175) and patients with LVEF ≥50% (group II; n = 545). Patients in group I were further divided according to whether additional ablation of non-PV triggers was performed (group IA; n = 88) or not (group IB; n = 87). Long-term ablation success off antiarrhythmic drugs after a single procedure was analyzed. Results Patients in group I had more non-PV triggers than did patients in group II (69.1% vs 26.6%; P
AB - Background Whether ablation of non-pulmonary vein (PV) triggers after pulmonary vein antrum isolation (PVAI) improves the long-term procedure outcome in patients with paroxysmal atrial fibrillation (PAF) and left ventricular systolic dysfunction is unknown. Objective We sought to evaluate whether a more extensive ablation procedure improves outcomes at follow-up. Methods Consecutive patients with PAF refractory to antiarrhythmic drugs presenting for PVAI were prospectively studied. Patients were categorized into 2 groups: patients with left ventricular ejection fraction (LVEF) ≤35% (group I; n = 175) and patients with LVEF ≥50% (group II; n = 545). Patients in group I were further divided according to whether additional ablation of non-PV triggers was performed (group IA; n = 88) or not (group IB; n = 87). Long-term ablation success off antiarrhythmic drugs after a single procedure was analyzed. Results Patients in group I had more non-PV triggers than did patients in group II (69.1% vs 26.6%; P
KW - Atrial fibrillation
KW - Catheter ablation
KW - Ejection fraction
KW - Heart failure
UR - http://www.scopus.com/inward/record.url?scp=84955471733&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955471733&partnerID=8YFLogxK
U2 - 10.1016/j.hrthm.2015.08.029
DO - 10.1016/j.hrthm.2015.08.029
M3 - Article
C2 - 26304713
AN - SCOPUS:84955471733
VL - 13
SP - 141
EP - 149
JO - Heart Rhythm
JF - Heart Rhythm
SN - 1547-5271
IS - 1
ER -