Impact of hospital volume on perioperative outcomes and costs of radical Cystectomy: Analysis of the Maryland Health Services Cost Review Commission database

Michael A. Gorin, Max Kates, Jeffrey K. Mullins, Phillip M. Pierorazio, Brian R. Matlaga, Mark P. Schoenberg, Trinity J. Bivalacqua

Research output: Contribution to journalArticle

14 Scopus citations


Introduction: The objective of this study was to evaluate the impact of hospital case volume on perioperative outcomes and costs of radical cystectomy (RC) after controlling for differences in patient case mix. Materials and methods: The Maryland Health Services Cost Review Commission database was queried for patients who underwent an open RC between 2000 and 2011. Patients were divided into tertiles based on hospital case volume. Groups were compared for differences in length of intensive care unit (ICU) stay, length of total hospital stay, rate of in-hospital deaths and procedure-related costs. Results: In total, 1620 patients underwent a RC during the study period. Of these patients, 457 (28.2%) underwent surgery at 37 low volume centers, 465 (28.7%) at six mid volume centers and 698 (43.1%) at a single high volume center. The mean case volume of each group was 1.1, 7.0 and 63.5 RC/center/year, respectively. After controlling for marked differences in patient case mix, having surgery at the single high-volume center was independently associated with a decrease in length of ICU stay (coefficient = -0.41 days, 95% CI -0.78-0.05, p = 0.03), in-hospital mortality (OR 0.18, 95% CI 0.04-0.80, p = 0.02) and total medical costs (coefficient = -2.91k USD, 95% CI -4.15-1.67, p < 0.001). Decreased total costs were driven by reductions in charges associated with the operating room, drugs, radiology tests, labs, supplies and physical/occupational therapy (all p < 0.001). Conclusions: Undergoing RC at a high volume medical center was associated with improved outcomes and reduced costs. These data support the centralization of RC to high volume centers.

Original languageEnglish (US)
Pages (from-to)7102-7107
Number of pages6
JournalCanadian Journal of Urology
Issue number1
StatePublished - Feb 25 2014
Externally publishedYes



  • Bladder cancer
  • Cost analysis
  • Outcomes
  • Radical cystectomy
  • Surgical volume

ASJC Scopus subject areas

  • Urology

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