Impact of horizontal aorta on procedural and clinical outcomes in second-generation transcatheter aortic valve implantation

Daniele Di Stefano, Antonio Colombo, Antonio Mangieri, Guglielmo Gallone, Georgios Tzanis, Alessandra Laricchia, Luca Baldetti, Anna Palmisano, Antonio Esposito, Francesco Gallo, Azeem Latib, Matteo Montorfano, Francesco Giannini

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Aims: The aim of this study was to evaluate the impact of a horizontal aorta (HA) on device success and short-term clinical outcomes of transcatheter aortic valve implantation (TAVI). Methods and results: We retrospectively assessed 547 consecutive patients treated with transfemoral second-generation non-balloon-expandable (NBE) (n=447) and balloon-expandable (BE) (n=100) TAVI for symptomatic severe aortic stenosis. Aortic angulation (AA) was evaluated with preprocedural computed tomography. Patients were dichotomised according to a previously established AA cut-point: HA group (AA ≥48°, n=230) and normal aorta (NA) group (AA <48°, n=317). Endpoints were considered according to the Valve Academic Research Consortium-2 definitions. Fluoroscopy time (32.8±16.4 vs 30.3±13.9 minutes, p=0.060) and radiation dose (kerma area product 120.8±99.7 vs 103.7±81.1 Gy·cm2, p=0.033) were higher in the HA group as compared to the NA group. No difference in device success was observed between patients with and without an HA (88.3% vs 88.0%, p=0.929). No differences in device success and 30-day outcomes were observed when comparing HA and NA patients, according to BE and NBE prostheses. Conclusions: The presence of an HA has no impact on device success and short-term clinical outcomes of TAVI with either second-generation NBE or BE devices.

Original languageEnglish (US)
Pages (from-to)E746-E756
JournalEuroIntervention
Volume15
Issue number9
DOIs
StatePublished - Oct 1 2019
Externally publishedYes

Keywords

  • Aortic stenosis
  • MSCT
  • TAVI

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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