Immunoglobulin M immunoblot for diagnosis of Borrelia burgdorferi infection in patients with acute facial palsy

Varsha K. Jain, Eileen Hilton, Joseph Maytal, Gary Dorante, Norman T. Ilowite, Sunil K. Sood

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

We used immunoblotting to improve the specificity of the serologic diagnosis of Lyme borreliosis in cases of acute facial palsy. Twelve of 15 patients (80%) with suspected Lyme borreliosis, versus 0 of 10 controls, were positive by immunoglobulin M immunoblotting of acute-phase sero and 3 were negative, including 2 with borderline enzyme immunoassay results. Immunoglobulin M immunoblotting is a useful test to confirm Borrelia burgdorferi infection in patients with acute facial palsy and a positive enzyme immunoassay result.

Original languageEnglish (US)
Pages (from-to)2033-2035
Number of pages3
JournalJournal of Clinical Microbiology
Volume34
Issue number8
DOIs
StatePublished - Aug 1996

ASJC Scopus subject areas

  • Microbiology (medical)

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