Immunoglobulin M immunoblot for diagnosis of Borrelia burgdorferi infection in patients with acute facial palsy

Varsha K. Jain, Eileen Hilton, Joseph Maytal, Gary Dorante, Norman T. Ilowite, Sunil K. Sood

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

We used immunoblotting to improve the specificity of the serologic diagnosis of Lyme borreliosis in cases of acute facial palsy. Twelve of 15 patients (80%) with suspected Lyme borreliosis, versus 0 of 10 controls, were positive by immunoglobulin M immunoblotting of acute-phase sero and 3 were negative, including 2 with borderline enzyme immunoassay results. Immunoglobulin M immunoblotting is a useful test to confirm Borrelia burgdorferi infection in patients with acute facial palsy and a positive enzyme immunoassay result.

Original languageEnglish (US)
Pages (from-to)2033-2035
Number of pages3
JournalJournal of Clinical Microbiology
Volume34
Issue number8
DOIs
StatePublished - Aug 1996

ASJC Scopus subject areas

  • Microbiology (medical)

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