Immune complex-mediated renal involvement in relapsing polychondritis

Luis R. Espinoza, Alan Richman, Tomas Bocanegra, Ileana L. Pina, Frank B. Vasey, Stephen I. Rifkin, Bernard F. Germain

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A patient with relapsing polychondritis who presented with rapidly progressive glomerulonephritis is described. This is the fourth case in which this association is reported. Crescentic glomerulonephritis was found on renal biopsy. Evidence for immunologic participation in the pathogenesis of this condition is suggested by the demonstration of circulating immune complexes, immunoglobulin and complement deposition by immunofluorescence, and electron dense deposits by electron microscopy of the kidney. Favorable response followed therapy with prednisone and dapsone.

Original languageEnglish (US)
Pages (from-to)181-183
Number of pages3
JournalThe American journal of medicine
Volume71
Issue number1
DOIs
StatePublished - 1981
Externally publishedYes

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Relapsing Polychondritis
Glomerulonephritis
Antigen-Antibody Complex
Kidney
Dapsone
Prednisone
Fluorescent Antibody Technique
Immunoglobulins
Electron Microscopy
Electrons
Biopsy
Therapeutics

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Espinoza, L. R., Richman, A., Bocanegra, T., Pina, I. L., Vasey, F. B., Rifkin, S. I., & Germain, B. F. (1981). Immune complex-mediated renal involvement in relapsing polychondritis. The American journal of medicine, 71(1), 181-183. https://doi.org/10.1016/0002-9343(81)90291-6

Immune complex-mediated renal involvement in relapsing polychondritis. / Espinoza, Luis R.; Richman, Alan; Bocanegra, Tomas; Pina, Ileana L.; Vasey, Frank B.; Rifkin, Stephen I.; Germain, Bernard F.

In: The American journal of medicine, Vol. 71, No. 1, 1981, p. 181-183.

Research output: Contribution to journalArticle

Espinoza, LR, Richman, A, Bocanegra, T, Pina, IL, Vasey, FB, Rifkin, SI & Germain, BF 1981, 'Immune complex-mediated renal involvement in relapsing polychondritis', The American journal of medicine, vol. 71, no. 1, pp. 181-183. https://doi.org/10.1016/0002-9343(81)90291-6
Espinoza, Luis R. ; Richman, Alan ; Bocanegra, Tomas ; Pina, Ileana L. ; Vasey, Frank B. ; Rifkin, Stephen I. ; Germain, Bernard F. / Immune complex-mediated renal involvement in relapsing polychondritis. In: The American journal of medicine. 1981 ; Vol. 71, No. 1. pp. 181-183.
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