Imaging monetary reward in pathological gamblers

Eric Hollander, Stefano Pallanti, Nicolo Baldini Rossi, Erica Sood, Bryann R. Baker, Monte S. Buchsbaum

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

We acquired two 18F-deoxyglucose positron emisssion tomography (PET) scans on seven unmedicated pathological gamblers, at least 7 days apart. Following an injection of 5 mCi FDG, subjects carried out a computer blackjack task for 35 min under two different reward conditions: monetary reward and computer game points only. Relative FDG metabolic rate was obtained from regions of interest in the prefrontal cortex, cingulate, striatum and visual cortex. Monetary reward blackjack was associated with significantly higher relative metabolic rate in the primary visual cortex (Brodmann area 17), the cingulate gryus (Brodmann area 24), the putamen and prefrontal areas 47 and 10, compared to blackjack playing for points only. No area tested showed a significant decrease. This pattern suggests heightened limbic and sensory activation in the gambling for money condition with increased emotional valence and greater risk and reward, and confirms the salience of monetary reward in the development of pathological gambling.

Original languageEnglish (US)
Pages (from-to)113-120
Number of pages8
JournalWorld Journal of Biological Psychiatry
Volume6
Issue number2
DOIs
StatePublished - 2005
Externally publishedYes

Fingerprint

Reward
Gambling
Gyrus Cinguli
Visual Cortex
Video Games
Putamen
Deoxyglucose
Prefrontal Cortex
Tomography
Electrons
Injections

Keywords

  • Blackjack
  • Imaging
  • Pathological gambling
  • PET
  • Reward

ASJC Scopus subject areas

  • Biological Psychiatry
  • Psychiatry and Mental health

Cite this

Hollander, E., Pallanti, S., Baldini Rossi, N., Sood, E., Baker, B. R., & Buchsbaum, M. S. (2005). Imaging monetary reward in pathological gamblers. World Journal of Biological Psychiatry, 6(2), 113-120. https://doi.org/10.1080/15622970510029768

Imaging monetary reward in pathological gamblers. / Hollander, Eric; Pallanti, Stefano; Baldini Rossi, Nicolo; Sood, Erica; Baker, Bryann R.; Buchsbaum, Monte S.

In: World Journal of Biological Psychiatry, Vol. 6, No. 2, 2005, p. 113-120.

Research output: Contribution to journalArticle

Hollander, E, Pallanti, S, Baldini Rossi, N, Sood, E, Baker, BR & Buchsbaum, MS 2005, 'Imaging monetary reward in pathological gamblers', World Journal of Biological Psychiatry, vol. 6, no. 2, pp. 113-120. https://doi.org/10.1080/15622970510029768
Hollander, Eric ; Pallanti, Stefano ; Baldini Rossi, Nicolo ; Sood, Erica ; Baker, Bryann R. ; Buchsbaum, Monte S. / Imaging monetary reward in pathological gamblers. In: World Journal of Biological Psychiatry. 2005 ; Vol. 6, No. 2. pp. 113-120.
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