Imaging findings in systemic childhood diseases presenting with dermatologic manifestations

Adam Z. Fink, Julia K. Gittler, Radhika N. Nakrani, Jonathan Alis, Einat Blumfield, Terry L. Levin

Research output: Contribution to journalReview article

Abstract

Purpose Many childhood diseases often present with skin abnormalities with which radiologists are largely unfamiliar. Knowledge of associated dermatologic manifestations may aid the radiologist in confirming the diagnosis and recommending targeted imaging of affected organs. Methods We review the imaging findings in childhood diseases associated with dermatologic manifestations. Findings Diseases include dermatologic findings which herald underlying malignancy (Neuroblastoma, leukemia/lymphoma, Langerhans cell histiocytosis),are associated with risk of malignancy (Epidermolysis Bullosa, basal cell nevus syndrome, Cowden's syndrome, Tuberous Sclerosis),or indicate a systemic inflammatory/immune disorder (Kawasaki's disease, Henoch Schonlein Purpura, systemic lupus erythematosus, scleroderma, sarcoidosis, dermatomyositis and immune thrombocytopenic purpura). Conclusion Familiarity with pertinent findings in childhood diseases presenting with dermatologic manifestations in childhood diseases aids the radiologist in confirming the diagnosis and guiding imaging workup.

Original languageEnglish (US)
Pages (from-to)17-36
Number of pages20
JournalClinical Imaging
Volume49
DOIs
StatePublished - May 1 2018

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Skin Abnormalities
Multiple Hamartoma Syndrome
Basal Cell Nevus Syndrome
Epidermolysis Bullosa
Schoenlein-Henoch Purpura
Langerhans Cell Histiocytosis
Mucocutaneous Lymph Node Syndrome
Tuberous Sclerosis
Dermatomyositis
Idiopathic Thrombocytopenic Purpura
Immune System Diseases
Sarcoidosis
Neuroblastoma
Systemic Lupus Erythematosus
Lymphoma
Neoplasms
Leukemia
Radiologists
Recognition (Psychology)

Keywords

  • Dermatology
  • Imaging
  • Pediatric

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Imaging findings in systemic childhood diseases presenting with dermatologic manifestations. / Fink, Adam Z.; Gittler, Julia K.; Nakrani, Radhika N.; Alis, Jonathan; Blumfield, Einat; Levin, Terry L.

In: Clinical Imaging, Vol. 49, 01.05.2018, p. 17-36.

Research output: Contribution to journalReview article

Fink, Adam Z. ; Gittler, Julia K. ; Nakrani, Radhika N. ; Alis, Jonathan ; Blumfield, Einat ; Levin, Terry L. / Imaging findings in systemic childhood diseases presenting with dermatologic manifestations. In: Clinical Imaging. 2018 ; Vol. 49. pp. 17-36.
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