Imaging findings in systemic childhood diseases presenting with dermatologic manifestations

Adam Z. Fink, Julia K. Gittler, Radhika N. Nakrani, Jonathan Alis, Einat Blumfield, Terry L. Levin

Research output: Contribution to journalReview article

Abstract

Purpose Many childhood diseases often present with skin abnormalities with which radiologists are largely unfamiliar. Knowledge of associated dermatologic manifestations may aid the radiologist in confirming the diagnosis and recommending targeted imaging of affected organs. Methods We review the imaging findings in childhood diseases associated with dermatologic manifestations. Findings Diseases include dermatologic findings which herald underlying malignancy (Neuroblastoma, leukemia/lymphoma, Langerhans cell histiocytosis),are associated with risk of malignancy (Epidermolysis Bullosa, basal cell nevus syndrome, Cowden's syndrome, Tuberous Sclerosis),or indicate a systemic inflammatory/immune disorder (Kawasaki's disease, Henoch Schonlein Purpura, systemic lupus erythematosus, scleroderma, sarcoidosis, dermatomyositis and immune thrombocytopenic purpura). Conclusion Familiarity with pertinent findings in childhood diseases presenting with dermatologic manifestations in childhood diseases aids the radiologist in confirming the diagnosis and guiding imaging workup.

Original languageEnglish (US)
Pages (from-to)17-36
Number of pages20
JournalClinical Imaging
Volume49
DOIs
StatePublished - May 1 2018

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Keywords

  • Dermatology
  • Imaging
  • Pediatric

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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