Idiopathic intestinal perforations in the newborn

An increasingly common entity

Gerard Weinberg, Sylvain Kleinhaus, Scott J. Boley

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Between 1982 and 1987 seven neonates ranging in age from 24 hours to 1 week were treated for idiopathic intestinal perforations at the Montefiore Medical Center, Albert Einstein College of Medicine. Four of the infants were born prematurely; three were full term. Five were being treated in an intensive care nursery when the perforration was diagnosed. All infants whose perforations were due to necrotizing enterocolitis, appendicitis, Hirschsprung's disease, meconium ileus, intestinal atresias, or drug therapy are excluded from the series. None of the infants had associated anomalies. The sites of the perforations were as follows: two in the jejunum, two in the ileum, one in the cecum, and two in the transverse colon. Six of the perforations were on the antimesenteric aspect of the bowel; one was on the mesenteric aspect. The sizes of the perforations ranged from pinhole to 1 cm in diameter. All the infants did well. Pathologic examination of the resected specimens failed to reveal an etiology for the perforations. There were no cases of duplication or muscular hypoplasia. We believe the etiology of this condition may be ischemic necrosis, secondary to a localized vascular accident in the wall of the affected viscus, but we do not have a good explanation for the upsurge in cases we are seeing.

Original languageEnglish (US)
Pages (from-to)1007-1008
Number of pages2
JournalJournal of Pediatric Surgery
Volume24
Issue number10
DOIs
StatePublished - 1989
Externally publishedYes

Fingerprint

Intestinal Perforation
Newborn Infant
Intestinal Atresia
Meconium
Hirschsprung Disease
Transverse Colon
Necrotizing Enterocolitis
Viscera
Cecum
Ileus
Nurseries
Appendicitis
Jejunum
Critical Care
Ileum
Accidents
Blood Vessels
Necrosis
Medicine
Drug Therapy

Keywords

  • Idiopathic intestinal perforation
  • newborn

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Idiopathic intestinal perforations in the newborn : An increasingly common entity. / Weinberg, Gerard; Kleinhaus, Sylvain; Boley, Scott J.

In: Journal of Pediatric Surgery, Vol. 24, No. 10, 1989, p. 1007-1008.

Research output: Contribution to journalArticle

Weinberg, Gerard ; Kleinhaus, Sylvain ; Boley, Scott J. / Idiopathic intestinal perforations in the newborn : An increasingly common entity. In: Journal of Pediatric Surgery. 1989 ; Vol. 24, No. 10. pp. 1007-1008.
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