Hypertension and renal diseases.

D. S. Baldwin, Joel Neugarten

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Experimental data are summarized that provide evidence that enhanced transmission of systemic hypertension to the glomerulus occurs in the setting of reduced renal mass. It is proposed that similar adaptive glomerular hemodynamic alterations occur in parenchymal renal disease in humans, favoring the development of intraorgan hypertension. Accelerated vascular and glomerular damage and functional deterioration result. Treatment of systemic hypertension with agents that reduce glomerular capillary pressure has been shown to ameliorate the manifestations of experimental glomerular disease. The importance of preventing hemodynamic injury to the arterioles and glomerular capillaries in the management of human renal disease is stressed.

Original languageEnglish (US)
Pages (from-to)186-191
Number of pages6
JournalAmerican Journal of Kidney Diseases
Volume10
Issue number3
StatePublished - Sep 1987
Externally publishedYes

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Renal Hypertension
Hypertension
Kidney
Hemodynamics
Arterioles
Human Development
Blood Vessels
Pressure
Wounds and Injuries

ASJC Scopus subject areas

  • Nephrology

Cite this

Hypertension and renal diseases. / Baldwin, D. S.; Neugarten, Joel.

In: American Journal of Kidney Diseases, Vol. 10, No. 3, 09.1987, p. 186-191.

Research output: Contribution to journalArticle

Baldwin, D. S. ; Neugarten, Joel. / Hypertension and renal diseases. In: American Journal of Kidney Diseases. 1987 ; Vol. 10, No. 3. pp. 186-191.
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