TY - JOUR
T1 - Hypertension and heart failure
T2 - Focus on high-risk populations
AU - Di Palo, Katherine E.
N1 - Publisher Copyright:
© 2020 Lippincott Williams and Wilkins. All rights reserved.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - Purpose of reviewHypertension is a common, modifiable precursor to heart failure. Lifetime risk for development varies across age, sex, race and ability to achieve adequate blood pressure control.Recent findingsAlthough meta-analyses seemingly support intensive blood pressure control to reduce incident heart failure, randomized clinical trials are limited and do not enroll a large number of female, minority, elderly or treatment-resistant patients. Heterogeneity further adds to complexity; however, enhanced cognizance of these disparities can aid clinicians in creating patient-centered care plans.SummaryHigh-risk populations constitute an overwhelming percentage of the comorbid disease burden. Future clinical trials must reflect this diverse population to truly determine appropriate blood pressure targets and pharmacotherapy to reduce cardiovascular events.
AB - Purpose of reviewHypertension is a common, modifiable precursor to heart failure. Lifetime risk for development varies across age, sex, race and ability to achieve adequate blood pressure control.Recent findingsAlthough meta-analyses seemingly support intensive blood pressure control to reduce incident heart failure, randomized clinical trials are limited and do not enroll a large number of female, minority, elderly or treatment-resistant patients. Heterogeneity further adds to complexity; however, enhanced cognizance of these disparities can aid clinicians in creating patient-centered care plans.SummaryHigh-risk populations constitute an overwhelming percentage of the comorbid disease burden. Future clinical trials must reflect this diverse population to truly determine appropriate blood pressure targets and pharmacotherapy to reduce cardiovascular events.
KW - elderly
KW - heart failure
KW - hypertension
KW - racial disparities
KW - resistant hypertension
KW - women
UR - http://www.scopus.com/inward/record.url?scp=85086480057&partnerID=8YFLogxK
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U2 - 10.1097/HCO.0000000000000739
DO - 10.1097/HCO.0000000000000739
M3 - Review article
C2 - 32452922
AN - SCOPUS:85086480057
SN - 0268-4705
VL - 35
SP - 381
EP - 388
JO - Current opinion in cardiology
JF - Current opinion in cardiology
IS - 4
ER -