Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal trancriptional regulatory region in an antifolate-resistant HeLa cell line

Medicine & Life Sciences

• human SLC46A1 protein 100%
• Proton-Coupled Folate Transporter 86%
• Folic Acid Antagonists 65%
• Nucleic Acid Regulatory Sequences 54%
• HeLa Cells 47%
• Cell Line 28%
• Luciferases 14%
• Methylation 14%
• Folic Acid 10%
• Decitabine 6%
• hydrogen sulfite 6%
• CpG Islands 6%
• Intestinal Absorption 6%
• Regulator Genes 5%
• Fluorescence In Situ Hybridization 5%
• Reporter Genes 5%
• Cytogenetics 5%
• Methotrexate 5%
• Genetic Promoter Regions 5%
• Open Reading Frames 5%
• Sequence Analysis 4%
• Transfection 4%
• Plasmids 4%
• Nucleotides 4%
• Genes 4%
• Central Nervous System 3%
• Gene Expression 3%
• Messenger RNA 3%
• Mutation 2%
• In Vitro Techniques 2%