Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

Xue Liang Du, Diane Edelstein, Luciano Rossetti, Ivan George Fantus, Howard Goldberg, Fuad Ziyadeh, Jie Wu, Michael Brownlee

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814 Scopus citations

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Medicine & Life Sciences