Human urokinase gene is located on the long arm of chromosome 10

P. Tripputi, F. Blasi, P. Verde, L. A. Cannizzaro, B. S. Emanuel, C. M. Croce

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Abstract

Urokinase is one of the two plasminogen activators that catalyze the conversion of inactive plasminogen to plasmin. By combining somatic cell genetics, in situ hybridization, and Southern hybridization, we localized the human urokinase gene on the distal third of the long arm (q24-qter) of chromosome 10.

Original languageEnglish (US)
Pages (from-to)4448-4452
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume82
Issue number13
DOIs
StatePublished - Dec 1 1985

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