Abstract
Transcriptionally active human papillomavirus type 6a (HPV-6a) DNA was detected in a lung carcinoma of a patient with recurrent laryngeal papillomatosis. The carcinoma contained episomal HPV-6a genomes that had a duplication of the upstream regulatory region, the late region and a portion of the early region. HPV-6a genomes found in benign laryngeal papillomas from the same patient did not contain this duplication. A role for the mutant molecules in the pathogenesis of the malignancy is suggested.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 423-428 |
| Number of pages | 6 |
| Journal | Journal of General Virology |
| Volume | 73 |
| Issue number | 2 |
| State | Published - 1992 |
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ASJC Scopus subject areas
- Immunology
- Virology
Cite this
Human papillomavirus type 6a DNA in the lung carcinoma of a patient with recurrent laryngeal papillomatosis is characterized by a partial duplication. / DiLorenzo, Teresa P.; Tamsen, A.; Abramson, A. L.; Steinberg, B. M.
In: Journal of General Virology, Vol. 73, No. 2, 1992, p. 423-428.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Human papillomavirus type 6a DNA in the lung carcinoma of a patient with recurrent laryngeal papillomatosis is characterized by a partial duplication
AU - DiLorenzo, Teresa P.
AU - Tamsen, A.
AU - Abramson, A. L.
AU - Steinberg, B. M.
PY - 1992
Y1 - 1992
N2 - Transcriptionally active human papillomavirus type 6a (HPV-6a) DNA was detected in a lung carcinoma of a patient with recurrent laryngeal papillomatosis. The carcinoma contained episomal HPV-6a genomes that had a duplication of the upstream regulatory region, the late region and a portion of the early region. HPV-6a genomes found in benign laryngeal papillomas from the same patient did not contain this duplication. A role for the mutant molecules in the pathogenesis of the malignancy is suggested.
AB - Transcriptionally active human papillomavirus type 6a (HPV-6a) DNA was detected in a lung carcinoma of a patient with recurrent laryngeal papillomatosis. The carcinoma contained episomal HPV-6a genomes that had a duplication of the upstream regulatory region, the late region and a portion of the early region. HPV-6a genomes found in benign laryngeal papillomas from the same patient did not contain this duplication. A role for the mutant molecules in the pathogenesis of the malignancy is suggested.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026516792&partnerID=8YFLogxK
M3 - Article
VL - 73
SP - 423
EP - 428
JO - Journal of General Virology
JF - Journal of General Virology
SN - 0022-1317
IS - 2
ER -