Human Papillomavirus Testing in Cervical Cancer Screening

Philip E. Castle; Miriam Cremer

doi:10.1016/j.ogc.2013.03.002

Human Papillomavirus Testing in Cervical Cancer Screening

Philip E. Castle, Miriam Cremer

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

Human papillomavirus (HPV) testing is more reliable and sensitive but less specific than Papanicolaou (Pap) testing/cervical cytology for the detection of cervical precancer and cancer. HPV-negative women are at lower risk of cervical cancer than Pap-negative women. In high-resource settings, HPV testing can be used to make cervical cancer prevention programs more efficient by focusing clinical attention on women who have HPV. In lower-resource settings, where Pap testing has not been sustained or widespread, new, lower-cost HPV tests may make cervical cancer screening feasible.

Original language	English (US)
Pages (from-to)	377-390
Number of pages	14
Journal	Obstetrics and Gynecology Clinics of North America
Volume	40
Issue number	2
DOIs	https://doi.org/10.1016/j.ogc.2013.03.002
State	Published - Jun 1 2013
Externally published	Yes

Keywords

Cervical cancer
Cervical intraepithelial neoplasia
Human papillomavirus (HPV)
Low-resource settings
Pap testing
Screening
Vaccination
Visual inspection after acetic acid (VIA)

ASJC Scopus subject areas

Obstetrics and Gynecology

Access to Document

10.1016/j.ogc.2013.03.002

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Cite this

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title = "Human Papillomavirus Testing in Cervical Cancer Screening",

abstract = "Human papillomavirus (HPV) testing is more reliable and sensitive but less specific than Papanicolaou (Pap) testing/cervical cytology for the detection of cervical precancer and cancer. HPV-negative women are at lower risk of cervical cancer than Pap-negative women. In high-resource settings, HPV testing can be used to make cervical cancer prevention programs more efficient by focusing clinical attention on women who have HPV. In lower-resource settings, where Pap testing has not been sustained or widespread, new, lower-cost HPV tests may make cervical cancer screening feasible.",

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AB - Human papillomavirus (HPV) testing is more reliable and sensitive but less specific than Papanicolaou (Pap) testing/cervical cytology for the detection of cervical precancer and cancer. HPV-negative women are at lower risk of cervical cancer than Pap-negative women. In high-resource settings, HPV testing can be used to make cervical cancer prevention programs more efficient by focusing clinical attention on women who have HPV. In lower-resource settings, where Pap testing has not been sustained or widespread, new, lower-cost HPV tests may make cervical cancer screening feasible.

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KW - Vaccination

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