Human papillomavirus deoxyribonucleic acid in adenocarcinoma and adenosquamous carcinoma of the uterine cervix

David Smotkin, Jonathan S. Berek, Yao S. Fu, Neville F. Hacker, Francis J. Major, Felix O. Wettstein

Research output: Contribution to journalArticle

76 Scopus citations

Abstract

This report describes the detection of human papillomavirus type 16 or 18 deoxyribonucleic acid (DNA) in nine of 15 invasive tumors of the cervix, including three squamous carcinomas, four adenosquamous carcinomas, one glassy cell carcinoma, and one adenocarcinoma. The viral DNA was identified by Southern blotting and DNA hybridization. Human papillomaviruses may play an etiologic role in the development of at least some adenocarcinomas and adenosquamous carcinomas as well as most squamous tumors of the cervix.

Original languageEnglish (US)
Pages (from-to)241-244
Number of pages4
JournalObstetrics and gynecology
Volume68
Issue number2
StatePublished - Aug 1986
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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  • Cite this

    Smotkin, D., Berek, J. S., Fu, Y. S., Hacker, N. F., Major, F. J., & Wettstein, F. O. (1986). Human papillomavirus deoxyribonucleic acid in adenocarcinoma and adenosquamous carcinoma of the uterine cervix. Obstetrics and gynecology, 68(2), 241-244.