Human papillomavirus and the risk of cervical cancer

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Human papillomavirus (HPV) is now recognized as the driving force behind the dysregulation of the cell cycle that underlies cervical malignant transformation. Although nearly all cervical cancers contain HPV genomes, the vast majority of HPVs are not oncogenic but merely induce benign lesions. Because progressive abnormalities take at least a decade to develop into invasive cancers, young women with low-grade lesions can often be managed with watchful waiting rather than ablative therapy.

Original languageEnglish (US)
Pages (from-to)103-111
Number of pages9
JournalHospital Practice
Volume34
Issue number12
StatePublished - Nov 15 1999

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Watchful Waiting
Human Genome
Uterine Cervical Neoplasms
Cell Cycle
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Human papillomavirus and the risk of cervical cancer. / Burk, Robert D.

In: Hospital Practice, Vol. 34, No. 12, 15.11.1999, p. 103-111.

Research output: Contribution to journalArticle

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