Human immunodeficiency virus infection among homeless men in a New York City shelter: Association with Mycobacterium tuberculosis infection

Ramon A. Torres, Sridhar Mani, Jeffrey Altholz, Philip W. Brickner

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

The human immunodeficiency virus (HIV) seroprevalence among a selected sample of 169 high-risk homeless men residing in a congregate shelter in New York City, NY, was 62%. Seropositivity for HIV correlated significantly with intravenous drug use (odds ratio, 3.3; 95% confidence interval, 1.4 to 4.4) and active tuberculosis (odds ratio, 7.0; 95% confidence interval, 3.4 to 13.5). Most cases of active tuberculosis were among homeless men with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex; and significant CD4 lymphocyte depletion was associated with active tuberculosis. Total time homeless correlated positively with active and latent tuberculosis infection. Compliance rates with return for HIV antibody test results, medications, and follow-up visits were 70%, suggesting a significant degree of knowledge, awareness, and personal concern regarding HIV infection among homeless men; yet 28% of homeless intravenous drug users continue active drug injection, despite HIV infection. Cohabitation in overcrowded congregate dormitories creates a risk of airborne transmission of tuberculosis, which is a common reactivation infection in HIV-seropositive homeless men. Medically appropriate housing should be provided to such homeless persons, and expanded HIV antibody testing, counseling, and medical services on site should be offered to residents of shelters.

Original languageEnglish (US)
Pages (from-to)2030-2036
Number of pages7
JournalArchives of Internal Medicine
Volume150
Issue number10
StatePublished - Oct 1990
Externally publishedYes

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Mycobacterium Infections
Virus Diseases
Mycobacterium tuberculosis
HIV
Tuberculosis
Acquired Immunodeficiency Syndrome
Odds Ratio
Confidence Intervals
Lymphocyte Depletion
Latent Tuberculosis
Homeless Persons
Antibodies
Seroepidemiologic Studies
Drug Users
Pharmaceutical Preparations
Counseling
Injections
Infection

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Human immunodeficiency virus infection among homeless men in a New York City shelter : Association with Mycobacterium tuberculosis infection. / Torres, Ramon A.; Mani, Sridhar; Altholz, Jeffrey; Brickner, Philip W.

In: Archives of Internal Medicine, Vol. 150, No. 10, 10.1990, p. 2030-2036.

Research output: Contribution to journalArticle

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