Historical perspective of peptidomics

Michael Schrader; Peter Schulz-Knappe; Lloyd D. Fricker

doi:10.1016/j.euprot.2014.02.014

Historical perspective of peptidomics

Michael Schrader, Peter Schulz-Knappe, Lloyd D. Fricker

Molecular Pharmacology

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

Peptides have been studied for over 100 years, but for most of this time the focus was on a specific peptide or peptides, and not on the general peptidome of a biological sample. In the 1990s, mass spectrometry techniques were developed for the analysis of proteins, usually after digestion into peptides. The field of peptidomics started soon after proteomics and has grown to over 600 publications that use the word "peptidomic" or "peptidomics". Although peptidomics is related to proteomics, there are fundamental differences. In this review, we discuss these differences along with the history of the field of peptidomics.

Original language	English (US)
Pages (from-to)	171-182
Number of pages	12
Journal	EuPA Open Proteomics
Volume	3
DOIs	https://doi.org/10.1016/j.euprot.2014.02.014
State	Published - Jun 2014

Keywords

Biomarker discovery
Neuropeptides
Peptide hormones
Peptide research
Peptidome
Peptidomic

ASJC Scopus subject areas

Biochemistry

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10.1016/j.euprot.2014.02.014

Cite this

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KW - Peptide hormones

KW - Peptide research

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Historical perspective of peptidomics

Abstract

Keywords

ASJC Scopus subject areas

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