Histological evaluation of the inferior epigastric artery in patients with known atherosclerosis

D. S. Schwartz, S. M. Factor, J. D. Schwartz, E. Petrosian, A. Blitz, D. McLoughlin, V. Tellis, R. Frame, R. F. Brodman

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Comparative histological studies have been performed on the various arterial conduits available for myocardial revascularization including the inferior epigastric artery which has recently become the focus of intense investigation. In this study, 10 patients with known risk factors for atherosclerotic disease had their inferior epigastric artery harvested and the entire specimen examined for the microscopical presence of atherosclerosis or its precursors. Histopathological findings that have been shown to be theoretically protective against the progression of atherosclerosis were observed. These include the paucity of fenestrae in the internal elastic lamina, no medical calcification, the absence of foam cells and the absence of intimal smooth muscle cells. No specimen had atherosclerotic disease and only 3 specimens showed changes consistent with minimal intimal hyperplasia. Morphometric analysis of the 3 diseased specimens revealed only minimal luminal narrowing. These findings suggest that the inferior epigastric artery may not be prone to atherosclerosis. Thus, the inferior epigastric artery appears to be a safe myocardial conduit and long-term patency can be anticipated.

Original languageEnglish (US)
Pages (from-to)438-441
Number of pages4
JournalEuropean Journal of Cardio-thoracic Surgery
Volume6
Issue number8
StatePublished - 1992

Fingerprint

Epigastric Arteries
Atherosclerosis
Tunica Intima
Foam Cells
Myocardial Revascularization
Smooth Muscle Myocytes
Hyperplasia

Keywords

  • Atherosclerosis
  • Histopathology
  • Inferior epigastric artery

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Schwartz, D. S., Factor, S. M., Schwartz, J. D., Petrosian, E., Blitz, A., McLoughlin, D., ... Brodman, R. F. (1992). Histological evaluation of the inferior epigastric artery in patients with known atherosclerosis. European Journal of Cardio-thoracic Surgery, 6(8), 438-441.

Histological evaluation of the inferior epigastric artery in patients with known atherosclerosis. / Schwartz, D. S.; Factor, S. M.; Schwartz, J. D.; Petrosian, E.; Blitz, A.; McLoughlin, D.; Tellis, V.; Frame, R.; Brodman, R. F.

In: European Journal of Cardio-thoracic Surgery, Vol. 6, No. 8, 1992, p. 438-441.

Research output: Contribution to journalArticle

Schwartz, DS, Factor, SM, Schwartz, JD, Petrosian, E, Blitz, A, McLoughlin, D, Tellis, V, Frame, R & Brodman, RF 1992, 'Histological evaluation of the inferior epigastric artery in patients with known atherosclerosis', European Journal of Cardio-thoracic Surgery, vol. 6, no. 8, pp. 438-441.
Schwartz DS, Factor SM, Schwartz JD, Petrosian E, Blitz A, McLoughlin D et al. Histological evaluation of the inferior epigastric artery in patients with known atherosclerosis. European Journal of Cardio-thoracic Surgery. 1992;6(8):438-441.
Schwartz, D. S. ; Factor, S. M. ; Schwartz, J. D. ; Petrosian, E. ; Blitz, A. ; McLoughlin, D. ; Tellis, V. ; Frame, R. ; Brodman, R. F. / Histological evaluation of the inferior epigastric artery in patients with known atherosclerosis. In: European Journal of Cardio-thoracic Surgery. 1992 ; Vol. 6, No. 8. pp. 438-441.
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