Histological evaluation of the inferior epigastric artery in patients with known atherosclerosis

D. S. Schwartz, S. M. Factor, J. D. Schwartz, E. Petrosian, A. Blitz, D. McLoughlin, V. Tellis, R. Frame, R. F. Brodman

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Comparative histological studies have been performed on the various arterial conduits available for myocardial revascularization including the inferior epigastric artery which has recently become the focus of intense investigation. In this study, 10 patients with known risk factors for atherosclerotic disease had their inferior epigastric artery harvested and the entire specimen examined for the microscopical presence of atherosclerosis or its precursors. Histopathological findings that have been shown to be theoretically protective against the progression of atherosclerosis were observed. These include the paucity of fenestrae in the internal elastic lamina, no medical calcification, the absence of foam cells and the absence of intimal smooth muscle cells. No specimen had atherosclerotic disease and only 3 specimens showed changes consistent with minimal intimal hyperplasia. Morphometric analysis of the 3 diseased specimens revealed only minimal luminal narrowing. These findings suggest that the inferior epigastric artery may not be prone to atherosclerosis. Thus, the inferior epigastric artery appears to be a safe myocardial conduit and long-term patency can be anticipated. Eur J Cardio-thorac Surg (1992) 6:438-441].

Original languageEnglish (US)
Pages (from-to)438-441
Number of pages4
JournalEuropean Journal of Cardio-thoracic Surgery
Volume6
Issue number8
DOIs
StatePublished - Aug 1992

Keywords

  • Atherosclerosis
  • Histopathology
  • Inferior epigastric artery

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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    Schwartz, D. S., Factor, S. M., Schwartz, J. D., Petrosian, E., Blitz, A., McLoughlin, D., Tellis, V., Frame, R., & Brodman, R. F. (1992). Histological evaluation of the inferior epigastric artery in patients with known atherosclerosis. European Journal of Cardio-thoracic Surgery, 6(8), 438-441. https://doi.org/10.1016/1010-7940(92)90069-A