Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia

Karine Darbinyan, Aditi Shastri, Anjali Budhathoki, Daniel Helbig, Rose Snyder, Kith Pradhan, Junaid Saleh-Esa, Noah Kornblum, Adam F. Binder, Swati Goel, Murali Janakiram, Olga Derman, Kira Gritsman, Ulrich G. Steidl, Ira Braunschweig, Amit K. Verma, Ioannis Mantzaris

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

SEER data and a Bronx validation cohort demonstrate that Hispanics present with AML at younger age but have shorter survival than whites.Increased frequency of high-risk mutations in Hispanics provides a potential biologic explanation for poorer outcomes in Hispanics.

Original languageEnglish (US)
Pages (from-to)2120-2123
Number of pages4
JournalBlood advances
Volume1
Issue number24
DOIs
StatePublished - Nov 14 2017

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Hispanic Americans
Acute Myeloid Leukemia
Mutation

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Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia. / Darbinyan, Karine; Shastri, Aditi; Budhathoki, Anjali; Helbig, Daniel; Snyder, Rose; Pradhan, Kith; Saleh-Esa, Junaid; Kornblum, Noah; Binder, Adam F.; Goel, Swati; Janakiram, Murali; Derman, Olga; Gritsman, Kira; Steidl, Ulrich G.; Braunschweig, Ira; Verma, Amit K.; Mantzaris, Ioannis.

In: Blood advances, Vol. 1, No. 24, 14.11.2017, p. 2120-2123.

Research output: Contribution to journalArticle

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AU - Darbinyan, Karine

AU - Shastri, Aditi

AU - Budhathoki, Anjali

AU - Helbig, Daniel

AU - Snyder, Rose

AU - Pradhan, Kith

AU - Saleh-Esa, Junaid

AU - Kornblum, Noah

AU - Binder, Adam F.

AU - Goel, Swati

AU - Janakiram, Murali

AU - Derman, Olga

AU - Gritsman, Kira

AU - Steidl, Ulrich G.

AU - Braunschweig, Ira

AU - Verma, Amit K.

AU - Mantzaris, Ioannis

PY - 2017/11/14

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N2 - SEER data and a Bronx validation cohort demonstrate that Hispanics present with AML at younger age but have shorter survival than whites.Increased frequency of high-risk mutations in Hispanics provides a potential biologic explanation for poorer outcomes in Hispanics.

AB - SEER data and a Bronx validation cohort demonstrate that Hispanics present with AML at younger age but have shorter survival than whites.Increased frequency of high-risk mutations in Hispanics provides a potential biologic explanation for poorer outcomes in Hispanics.

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