High frequency (140 GHz) dynamic nuclear polarization: Polarization transfer to a solute in frozen aqueous solution

Gary J. Gerfen, L. R. Becerra, D. A. Hall, R. G. Griffin, R. J. Temkin, D. J. Singel

Research output: Contribution to journalArticle

135 Citations (Scopus)

Abstract

Dynamic nuclear polarization (DNP) transfers the large polarization of unpaired electrons to nuclei and thus significantly enhances the signal strength in nuclear magnetic resonance (NMR) spectroscopy. High frequency/field (140 GHz/5 T) DNP has been implemented in solid state NMR experiments using a nitroxide radical as the paramagnetic polarizing agent in a watenglycerol frozen solution. The 1H and 13C NMR signal strengths of both the solvent and an amino acid solute have been enhanced by a factor of 185, which represents a reduction of >102 in sample size requirements or >104 in signal acquisition time.

Original languageEnglish (US)
Pages (from-to)9494-9497
Number of pages4
JournalJournal of Chemical Physics
Volume102
Issue number24
StatePublished - 1995
Externally publishedYes

Fingerprint

solutes
Polarization
aqueous solutions
nuclear magnetic resonance
polarization
Nuclear magnetic resonance
magnetic resonance spectroscopy
Nuclear magnetic resonance spectroscopy
amino acids
acquisition
solid state
Amino Acids
requirements
nuclei
Electrons
electrons
Experiments
nitroxyl

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Gerfen, G. J., Becerra, L. R., Hall, D. A., Griffin, R. G., Temkin, R. J., & Singel, D. J. (1995). High frequency (140 GHz) dynamic nuclear polarization: Polarization transfer to a solute in frozen aqueous solution. Journal of Chemical Physics, 102(24), 9494-9497.

High frequency (140 GHz) dynamic nuclear polarization : Polarization transfer to a solute in frozen aqueous solution. / Gerfen, Gary J.; Becerra, L. R.; Hall, D. A.; Griffin, R. G.; Temkin, R. J.; Singel, D. J.

In: Journal of Chemical Physics, Vol. 102, No. 24, 1995, p. 9494-9497.

Research output: Contribution to journalArticle

Gerfen, GJ, Becerra, LR, Hall, DA, Griffin, RG, Temkin, RJ & Singel, DJ 1995, 'High frequency (140 GHz) dynamic nuclear polarization: Polarization transfer to a solute in frozen aqueous solution', Journal of Chemical Physics, vol. 102, no. 24, pp. 9494-9497.
Gerfen, Gary J. ; Becerra, L. R. ; Hall, D. A. ; Griffin, R. G. ; Temkin, R. J. ; Singel, D. J. / High frequency (140 GHz) dynamic nuclear polarization : Polarization transfer to a solute in frozen aqueous solution. In: Journal of Chemical Physics. 1995 ; Vol. 102, No. 24. pp. 9494-9497.
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