HHV-8 and AIDS-related CNS lymphoma

Susan Morgello, Michele Tagliati, Michelle R. Ewart

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Human herpesvirus 8 (HHV-8), the Kaposi's sarcoma (KS)-associated herpesvirus, is closely related to the transforming Epstein-Barr virus (EBV) and may be detected in AIDS-related, EBV-containing, body-cavity-based lymphomas. Accordingly, we analyzed 27 EBV-positive, AIDS-related CNS lymphomas for HHV-8 sequences. Only one tumor yielded HHV-8 sequences; this tumor arose in a patient with concomitant systemic lymphoma and a history of KS. We conclude that HHV-8 is unlikely to have a major role in the pathogenesis of AIDS-related, EBV-associated CNS lymphomas.

Original languageEnglish (US)
Pages (from-to)1333-1335
Number of pages3
JournalNeurology
Volume48
Issue number5
StatePublished - May 1997
Externally publishedYes

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AIDS-Related Lymphoma
Human Herpesvirus 8
Human Herpesvirus 4
Lymphoma
Acquired Immunodeficiency Syndrome
Kaposi's Sarcoma
Neoplasms

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Morgello, S., Tagliati, M., & Ewart, M. R. (1997). HHV-8 and AIDS-related CNS lymphoma. Neurology, 48(5), 1333-1335.

HHV-8 and AIDS-related CNS lymphoma. / Morgello, Susan; Tagliati, Michele; Ewart, Michelle R.

In: Neurology, Vol. 48, No. 5, 05.1997, p. 1333-1335.

Research output: Contribution to journalArticle

Morgello, S, Tagliati, M & Ewart, MR 1997, 'HHV-8 and AIDS-related CNS lymphoma', Neurology, vol. 48, no. 5, pp. 1333-1335.
Morgello S, Tagliati M, Ewart MR. HHV-8 and AIDS-related CNS lymphoma. Neurology. 1997 May;48(5):1333-1335.
Morgello, Susan ; Tagliati, Michele ; Ewart, Michelle R. / HHV-8 and AIDS-related CNS lymphoma. In: Neurology. 1997 ; Vol. 48, No. 5. pp. 1333-1335.
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