TY - JOUR
T1 - Heterogeneous Coding of Temporally Discounted Values in the Dorsal and Ventral Striatum during Intertemporal Choice
AU - Cai, Xinying
AU - Kim, Soyoun
AU - Lee, Daeyeol
N1 - Funding Information:
We thank Mark Hammond and Patrice Kurnath for technical assistance. This study was supported by the National Institute of Health (RL1 DA024855, P01 NS048328, and P30 EY000785).
PY - 2011/1/13
Y1 - 2011/1/13
N2 - In choosing between different rewards expected after unequal delays, humans and animals often prefer the smaller but more immediate reward, indicating that the subjective value or utility of reward is depreciated according to its delay. Here, we show that neurons in the primate caudate nucleus and ventral striatum modulate their activity according to temporally discounted values of rewards with a similar time course. However, neurons in the caudate nucleus encoded the difference in the temporally discounted values of the two alternative targets more reliably than neurons in the ventral striatum. In contrast, neurons in the ventral striatum largely encoded the sum of the temporally discounted values, and therefore, the overall goodness of available options. These results suggest a more pivotal role for the dorsal striatum in action selection during intertemporal choice.
AB - In choosing between different rewards expected after unequal delays, humans and animals often prefer the smaller but more immediate reward, indicating that the subjective value or utility of reward is depreciated according to its delay. Here, we show that neurons in the primate caudate nucleus and ventral striatum modulate their activity according to temporally discounted values of rewards with a similar time course. However, neurons in the caudate nucleus encoded the difference in the temporally discounted values of the two alternative targets more reliably than neurons in the ventral striatum. In contrast, neurons in the ventral striatum largely encoded the sum of the temporally discounted values, and therefore, the overall goodness of available options. These results suggest a more pivotal role for the dorsal striatum in action selection during intertemporal choice.
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U2 - 10.1016/j.neuron.2010.11.041
DO - 10.1016/j.neuron.2010.11.041
M3 - Article
C2 - 21220107
AN - SCOPUS:78650958482
SN - 0896-6273
VL - 69
SP - 170
EP - 182
JO - Neuron
JF - Neuron
IS - 1
ER -