Herpes simplex and varicella-zoster viruses

William J. Muller, Betsy C. Herold

Research output: Chapter in Book/Report/Conference proceedingChapter


Herpes simplex virus and varicella-zoster virus are common causes of infection in humans and persist in the host for life. The clinical significance of these viruses in oncology and transplant patients is related in part to the relative importance of cellular immunity for controlling replication in the host, as these patients often receive treatment that impairs these responses. This chapter reviews the current status of the epidemiology, clinical manifestations, diagnosis, treatment, and prevention of infections caused by herpes simplex virus and varicella-zoster virus in pediatric oncology, stem cell, and solid organ transplant patients.

Original languageEnglish (US)
Title of host publicationPediatric Transplant and Oncology Infectious Diseases
ISBN (Electronic)9780323641982
StatePublished - Jan 1 2020
Externally publishedYes


  • Herpes simplex virus
  • Oncology
  • Pediatrics
  • Solid organ transplantation
  • Stem cell transplantation
  • Varicella-zoster virus

ASJC Scopus subject areas

  • Medicine(all)


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