TY - JOUR
T1 - Hepatitis B virus and renal transplantation
AU - Kalia, Harmit
AU - Fabrizi, Fabrizio
AU - Martin, Paul
PY - 2011/7
Y1 - 2011/7
N2 - Hepatitis B virus (HBV) infection remains an important cause of liver disease in the renal transplant (RT) population, potentially diminishing survival. Consequences of HBV infection after RT include progression to decompensated cirrhosis and an increased risk of hepatocellular carcinoma. Although precautions initially recommended by the Centers for Diseases Control and Prevention 30 years ago have substantially reduced HBV transmission within hemodialysis units, acute HBV outbreaks continue to be reported in patients with chronic kidney disease on maintenance hemodialysis. In addition, immigration from areas of high HBV prevalence implies that HBV-infected organs with chronic kidney disease will continue to enter the RT pool. Fortunately, the advent of oral therapy for HBV infection now reduces the risk of HBV progression post-RT.
AB - Hepatitis B virus (HBV) infection remains an important cause of liver disease in the renal transplant (RT) population, potentially diminishing survival. Consequences of HBV infection after RT include progression to decompensated cirrhosis and an increased risk of hepatocellular carcinoma. Although precautions initially recommended by the Centers for Diseases Control and Prevention 30 years ago have substantially reduced HBV transmission within hemodialysis units, acute HBV outbreaks continue to be reported in patients with chronic kidney disease on maintenance hemodialysis. In addition, immigration from areas of high HBV prevalence implies that HBV-infected organs with chronic kidney disease will continue to enter the RT pool. Fortunately, the advent of oral therapy for HBV infection now reduces the risk of HBV progression post-RT.
UR - http://www.scopus.com/inward/record.url?scp=79959495777&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79959495777&partnerID=8YFLogxK
U2 - 10.1016/j.trre.2011.02.001
DO - 10.1016/j.trre.2011.02.001
M3 - Article
C2 - 21530218
AN - SCOPUS:79959495777
SN - 0955-470X
VL - 25
SP - 102
EP - 109
JO - Transplantation Reviews
JF - Transplantation Reviews
IS - 3
ER -