TY - JOUR
T1 - Hepatitis B and End-Stage Liver Disease
AU - Weisberg, Ilan S.
AU - Brown, Robert S.
AU - Sigal, Samuel H.
PY - 2007/11
Y1 - 2007/11
N2 - Hepatitis B virus (HBV) is the most common cause of chronic hepatitis and end-stage liver disease worldwide. Untreated, chronic hepatitis B acquired early in life results in cirrhosis, liver failure, or hepatocellular carcinoma in up to 40% of individuals. Until recently, the options for a patient who had end-stage hepatitis B cirrhosis were severely limited, but during the past 15 years great strides have been made in prevention and treatment of hepatitis B cirrhosis. This article reviews recent advances in the understanding of the natural history, prevention, and medical management of HBV-related end-stage liver disease.
AB - Hepatitis B virus (HBV) is the most common cause of chronic hepatitis and end-stage liver disease worldwide. Untreated, chronic hepatitis B acquired early in life results in cirrhosis, liver failure, or hepatocellular carcinoma in up to 40% of individuals. Until recently, the options for a patient who had end-stage hepatitis B cirrhosis were severely limited, but during the past 15 years great strides have been made in prevention and treatment of hepatitis B cirrhosis. This article reviews recent advances in the understanding of the natural history, prevention, and medical management of HBV-related end-stage liver disease.
UR - http://www.scopus.com/inward/record.url?scp=35548946090&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=35548946090&partnerID=8YFLogxK
U2 - 10.1016/j.cld.2007.08.009
DO - 10.1016/j.cld.2007.08.009
M3 - Review article
C2 - 17981234
AN - SCOPUS:35548946090
SN - 1089-3261
VL - 11
SP - 893
EP - 916
JO - Clinics in Liver Disease
JF - Clinics in Liver Disease
IS - 4
ER -
